TY - JOUR
T1 - The development of valid subtypes for depression in primary care settings
T2 - A preliminary study using an explanatory model approach
AU - Karasz, Alison
PY - 2008/4
Y1 - 2008/4
N2 - A persistent theme in the debate on the classification of depressive disorders is the distinction between biological and environmental depressions. Despite decades of research, there remains little consensus on how to distinguish between depressive subtypes. This preliminary study describes a method that could be useful, if implemented on a larger scale, in the development of valid subtypes of depression in primary care settings, using explanatory models of depressive illness. Seventeen depressed Hispanic patients at an inner city general practice participated in explanatory model interviews. Participants generated illness narratives, which included details about symptoms, cause, course, impact, health seeking, and anticipated outcome. Two distinct subtypes emerged from the analysis. The internal model subtype was characterized by internal attributions, specifically the notion of an "injured self." The external model subtype conceptualized depression as a reaction to life situations. Each subtype was associated with a distinct constellation of clinical features and health seeking experiences. Future directions for research using explanatory models to establish depressive subtypes are explored.
AB - A persistent theme in the debate on the classification of depressive disorders is the distinction between biological and environmental depressions. Despite decades of research, there remains little consensus on how to distinguish between depressive subtypes. This preliminary study describes a method that could be useful, if implemented on a larger scale, in the development of valid subtypes of depression in primary care settings, using explanatory models of depressive illness. Seventeen depressed Hispanic patients at an inner city general practice participated in explanatory model interviews. Participants generated illness narratives, which included details about symptoms, cause, course, impact, health seeking, and anticipated outcome. Two distinct subtypes emerged from the analysis. The internal model subtype was characterized by internal attributions, specifically the notion of an "injured self." The external model subtype conceptualized depression as a reaction to life situations. Each subtype was associated with a distinct constellation of clinical features and health seeking experiences. Future directions for research using explanatory models to establish depressive subtypes are explored.
KW - Classification
KW - Conceptual models
KW - Depression
KW - Explanatory model
KW - Illness representation
KW - Subtypes
UR - http://www.scopus.com/inward/record.url?scp=42249109842&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=42249109842&partnerID=8YFLogxK
U2 - 10.1097/NMD.0b013e31816a496e
DO - 10.1097/NMD.0b013e31816a496e
M3 - Article
C2 - 18414123
AN - SCOPUS:42249109842
SN - 0022-3018
VL - 196
SP - 289
EP - 296
JO - Journal of Nervous and Mental Disease
JF - Journal of Nervous and Mental Disease
IS - 4
ER -