The development of audiovisual multisensory integration across childhood and early adolescence: A high-density electrical mapping study

Alice B. Brandwein, John J. Foxe, Natalie N. Russo, Ted S. Altschuler, Hilary Gomes, Sophie Molholm

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

The integration of multisensory information is essential to forming meaningful representations of the environment. Adults benefit from related multisensory stimuli but the extent to which the ability to optimally integrate multisensory inputs for functional purposes is present in children has not been extensively examined. Using a cross-sectional approach, high-density electrical mapping of event-related potentials (ERPs) was combined with behavioral measures to characterize neurodevelopmental changes in basic audiovisual (AV) integration from middle childhood through early adulthood. The data indicated a gradual fine-tuning of multisensory facilitation of performance on an AV simple reaction time task (as indexed by race model violation), which reaches mature levels by about 14 years of age. They also revealed a systematic relationship between age and the brain processes underlying multisensory integration (MSI) in the time frame of the auditory N1 ERP component (∼120 ms). A significant positive correlation between behavioral and neurophysiological measures of MSI suggested that the underlying brain processes contributed to the fine-tuning of multisensory facilitation of behavior that was observed over middle childhood. These findings are consistent with protracted plasticity in a dynamic system and provide a starting point from which future studies can begin to examine the developmental course of multisensory processing in clinical populations.

Original languageEnglish (US)
Pages (from-to)1042-1055
Number of pages14
JournalCerebral Cortex
Volume21
Issue number5
DOIs
StatePublished - May 2011

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Evoked Potentials
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Keywords

  • children
  • cross-modal
  • development, electrophysiology
  • ERP
  • multisensory integration

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

Cite this

The development of audiovisual multisensory integration across childhood and early adolescence : A high-density electrical mapping study. / Brandwein, Alice B.; Foxe, John J.; Russo, Natalie N.; Altschuler, Ted S.; Gomes, Hilary; Molholm, Sophie.

In: Cerebral Cortex, Vol. 21, No. 5, 05.2011, p. 1042-1055.

Research output: Contribution to journalArticle

Brandwein, Alice B. ; Foxe, John J. ; Russo, Natalie N. ; Altschuler, Ted S. ; Gomes, Hilary ; Molholm, Sophie. / The development of audiovisual multisensory integration across childhood and early adolescence : A high-density electrical mapping study. In: Cerebral Cortex. 2011 ; Vol. 21, No. 5. pp. 1042-1055.
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