TY - JOUR
T1 - The cytoskeleton and mRNA localization
AU - Singer, Robert H.
PY - 1992/2
Y1 - 1992/2
N2 - The localization of mRNA appears to facilitate protein sorting, so that proteins are synthesized in specific cellular regions. The spatial information on the mRNA may be transduced by proteins that recognize specific localizing sequences on the 3′ end and then chaperone the mRNA, presumably along filaments, to its destination. Additional sequences such as poly(A), or the nascent chains of cytoskeleton-associated proteins, may then anchor mRNAs on the cytoskeleton.
AB - The localization of mRNA appears to facilitate protein sorting, so that proteins are synthesized in specific cellular regions. The spatial information on the mRNA may be transduced by proteins that recognize specific localizing sequences on the 3′ end and then chaperone the mRNA, presumably along filaments, to its destination. Additional sequences such as poly(A), or the nascent chains of cytoskeleton-associated proteins, may then anchor mRNAs on the cytoskeleton.
UR - http://www.scopus.com/inward/record.url?scp=0026816348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026816348&partnerID=8YFLogxK
U2 - 10.1016/0955-0674(92)90053-F
DO - 10.1016/0955-0674(92)90053-F
M3 - Article
C2 - 1558749
AN - SCOPUS:0026816348
SN - 0955-0674
VL - 4
SP - 15
EP - 19
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
IS - 1
ER -