The cytoskeleton and mRNA localization

Research output: Contribution to journalArticle

141 Scopus citations

Abstract

The localization of mRNA appears to facilitate protein sorting, so that proteins are synthesized in specific cellular regions. The spatial information on the mRNA may be transduced by proteins that recognize specific localizing sequences on the 3′ end and then chaperone the mRNA, presumably along filaments, to its destination. Additional sequences such as poly(A), or the nascent chains of cytoskeleton-associated proteins, may then anchor mRNAs on the cytoskeleton.

Original languageEnglish (US)
Pages (from-to)15-19
Number of pages5
JournalCurrent Opinion in Cell Biology
Volume4
Issue number1
DOIs
StatePublished - Feb 1992
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology

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