Taxol induced microtubule formations in fibroblasts of fetal mouse dorsal root ganglion-spinal cord cultures

E. B. Masurovsky, E. R. Peterson, S. M. Crain, Susan Band Horwitz

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Taxol engenders the formation of two types of unusual ordered arrays of microtubules (MT) in fibroblasts of mouse dorsal root ganglion-spinal cord explant cultures. One consists of lattice-like arrangements of MTs interdigitating with filamentous elements in the cytoplasm. The other of MTs arrayed along endoplasmic reticulum (ER) cisternae at regular ~30 nm intervals. Short linear elements, presumably proteinaceous, extend between the MTs and ER cisternae.

Original languageEnglish (US)
Pages (from-to)213-216
Number of pages4
JournalBiology of the Cell
Volume46
Issue number2
StatePublished - 1982

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Spinal Ganglia
Paclitaxel
Microtubules
Endoplasmic Reticulum
Spinal Cord
Fibroblasts
Cytoplasm

ASJC Scopus subject areas

  • Cell Biology

Cite this

Taxol induced microtubule formations in fibroblasts of fetal mouse dorsal root ganglion-spinal cord cultures. / Masurovsky, E. B.; Peterson, E. R.; Crain, S. M.; Band Horwitz, Susan.

In: Biology of the Cell, Vol. 46, No. 2, 1982, p. 213-216.

Research output: Contribution to journalArticle

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