Tailor-made monoclonal antibodies

R. A. DePinho, L. B. Feldman, Matthew D. Scharff

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Monoclonal antibodies, potentially powerful diagnostic and therapeutic reagents, are having a significant impact in basic and clinical research. Some persisting problems must be solved, however, in order to realize the potential of this technology. We review the basic biology of antibody molecules and the genes that encode them, and discuss how this knowledge can be applied to make more effective monoclonal antibodies.

Original languageEnglish (US)
Pages (from-to)225-233
Number of pages9
JournalAnnals of Internal Medicine
Volume104
Issue number2
StatePublished - 1986

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Monoclonal Antibodies
Technology
Antibodies
Research
Genes
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

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DePinho, R. A., Feldman, L. B., & Scharff, M. D. (1986). Tailor-made monoclonal antibodies. Annals of Internal Medicine, 104(2), 225-233.

Tailor-made monoclonal antibodies. / DePinho, R. A.; Feldman, L. B.; Scharff, Matthew D.

In: Annals of Internal Medicine, Vol. 104, No. 2, 1986, p. 225-233.

Research output: Contribution to journalArticle

DePinho, RA, Feldman, LB & Scharff, MD 1986, 'Tailor-made monoclonal antibodies', Annals of Internal Medicine, vol. 104, no. 2, pp. 225-233.
DePinho RA, Feldman LB, Scharff MD. Tailor-made monoclonal antibodies. Annals of Internal Medicine. 1986;104(2):225-233.
DePinho, R. A. ; Feldman, L. B. ; Scharff, Matthew D. / Tailor-made monoclonal antibodies. In: Annals of Internal Medicine. 1986 ; Vol. 104, No. 2. pp. 225-233.
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