Synthesis of melanin pigment by Candida albicans in vitro and during infection

Rachael Morris-Jones, Beatriz L. Gomez, Soraya Diez, Martha Uran, Stephen D. Morris-Jones, Arturo Casadevall, Joshua D. Nosanchuk, Andrew J. Hamilton

Research output: Contribution to journalArticle

52 Scopus citations

Abstract

Melanins are implicated in the pathogenesis of several important human diseases. This study confirmed the presence of melanin particles in Candida albicans in vitro and during infection. Dark particles were isolated from the digestion of C. albicans cultures and from infected tissue, as established by electron microscopy and immunofluorescence techniques.

Original languageEnglish (US)
Pages (from-to)6147-6150
Number of pages4
JournalInfection and immunity
Volume73
Issue number9
DOIs
StatePublished - Sep 2005

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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    Morris-Jones, R., Gomez, B. L., Diez, S., Uran, M., Morris-Jones, S. D., Casadevall, A., Nosanchuk, J. D., & Hamilton, A. J. (2005). Synthesis of melanin pigment by Candida albicans in vitro and during infection. Infection and immunity, 73(9), 6147-6150. https://doi.org/10.1128/IAI.73.9.6147-6150.2005