Sympatholytic agents

Yury Khelemsky, Karina Gritsenko, Christopher Curatolo

Research output: Chapter in Book/Report/Conference proceedingChapter


Sympatholytic drugs are agents that decrease the activity of the sympathetic nervous system (SNS). This is accomplished via a variety of mechanisms that most commonly include adrenergic receptor blockade (e.g., a and β adrenergic receptor antagonism) as well as specific receptor agonism (i.e., a2 adrenergic receptor agonism) (1). The SNS signal, however, may be blocked in other ways (e.g., peripheral ganglionic blockade) (2).

Original languageEnglish (US)
Title of host publicationPain Medicine
Subtitle of host publicationAn Essential Review
PublisherSpringer International Publishing
Number of pages3
ISBN (Electronic)9783319431338
ISBN (Print)9783319431314
StatePublished - Jan 1 2017


  • Acute panic performance anxiety
  • Adrenergic receptor antagonism
  • Complex regional pain syndrome
  • Drug interactions
  • Migraine
  • Nightmares
  • Post-traumatic stress disorder
  • Side effects
  • Weaning

ASJC Scopus subject areas

  • Medicine(all)


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