Susceptibilities of bacterial and fungal urinary tract isolates to desferrioxamine

F. D. Lowy, S. Pollack, N. Fadl-Allah, N. H. Steigbigel

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Desferrioxamine, a safe and effective iron chelator, was evaluated for its antibacterial and antifungal activity. The susceptibilities of 124 urinary tract isolates and 28 clinical isolates of Neisseria gonorrhoeae to desferrioxamine concentrations that are readily achievable in urine were determined. Of all isolates, 27% were inhibited by a concentration of ≤12.5 mM. Proteus mirabilis and N. gonorrhoeae isolates were particularly susceptible to the chelator. Desferrioxamine appears to have limited potential as an antibacterial agent.

Original languageEnglish (US)
Pages (from-to)375-376
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume25
Issue number3
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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