Surgical treatment options and management strategies of metastatic renal cell carcinoma to the lumbar spinal nerve roots

Christian Strong, Vijay Yanamadala, Arjun Khanna, Brian P. Walcott, Brian V. Nahed, Lawrence F. Borges, Jean Valery C.E. Coumans

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Spinal nerve root metastasis of renal cell carcinoma is a rare occurrence. In addition to treatment of the primary lesion, surgical resection of the nerve root metastasis, occasionally with sacrifice of the involved nerve, is the accepted standard of treatment. Resection often resolves presenting motor and pain symptoms due to relief of neural compression. We describe two patients with nerve root metastasis of renal cell carcinoma and their management. While locally advanced and metastatic renal cell carcinoma has been shown to be chemo- and radio-resistant, immunotherapy is a promising treatment. Given the high prevalence of systemic disease in patients with intradural metastases, systemic (and possibly intracranial) imaging can be used to identify other potential areas of disease.

Original languageEnglish (US)
Pages (from-to)1546-1549
Number of pages4
JournalJournal of Clinical Neuroscience
Volume20
Issue number11
DOIs
StatePublished - Nov 2013
Externally publishedYes

Keywords

  • Cauda equina
  • Intradural
  • Metastasis
  • Nerve root
  • Renal
  • Spine

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

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