Suppressor cells in the graft vs host reaction

J. A. Hardin, T. M. Chused, A. D. Steinberg

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

It is shown that a population of cells exists in the spleen of 6 week old NZB/W mice, capable of suppressing the GVH reactivity of 25 week old spleen cells. Thymus cells of 6 week old NZB/W mice also suppressed the GVH response. Two T cells (effector and amplifier) have previously been shown to cooperate in the GVH reaction. Although a number of interpretations may be offered, one possibility is that a third type of T cell, a suppressor cell, may also be involved in the regulation of this cell mediated immune reaction.

Original languageEnglish (US)
Pages (from-to)650-651
Number of pages2
JournalJournal of Immunology
Volume111
Issue number2
StatePublished - 1973
Externally publishedYes

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Graft vs Host Reaction
Inbred NZB Mouse
Spleen
T-Lymphocytes
Thymus Gland
Population

ASJC Scopus subject areas

  • Immunology

Cite this

Hardin, J. A., Chused, T. M., & Steinberg, A. D. (1973). Suppressor cells in the graft vs host reaction. Journal of Immunology, 111(2), 650-651.

Suppressor cells in the graft vs host reaction. / Hardin, J. A.; Chused, T. M.; Steinberg, A. D.

In: Journal of Immunology, Vol. 111, No. 2, 1973, p. 650-651.

Research output: Contribution to journalArticle

Hardin, JA, Chused, TM & Steinberg, AD 1973, 'Suppressor cells in the graft vs host reaction', Journal of Immunology, vol. 111, no. 2, pp. 650-651.
Hardin JA, Chused TM, Steinberg AD. Suppressor cells in the graft vs host reaction. Journal of Immunology. 1973;111(2):650-651.
Hardin, J. A. ; Chused, T. M. ; Steinberg, A. D. / Suppressor cells in the graft vs host reaction. In: Journal of Immunology. 1973 ; Vol. 111, No. 2. pp. 650-651.
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