Suppressor cells in the graft vs host reaction

J. A. Hardin, T. M. Chused, A. D. Steinberg

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61 Scopus citations

Abstract

It is shown that a population of cells exists in the spleen of 6 week old NZB/W mice, capable of suppressing the GVH reactivity of 25 week old spleen cells. Thymus cells of 6 week old NZB/W mice also suppressed the GVH response. Two T cells (effector and amplifier) have previously been shown to cooperate in the GVH reaction. Although a number of interpretations may be offered, one possibility is that a third type of T cell, a suppressor cell, may also be involved in the regulation of this cell mediated immune reaction.

Original languageEnglish (US)
Pages (from-to)650-651
Number of pages2
JournalJournal of Immunology
Volume111
Issue number2
StatePublished - Jan 1 1973

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Hardin, J. A., Chused, T. M., & Steinberg, A. D. (1973). Suppressor cells in the graft vs host reaction. Journal of Immunology, 111(2), 650-651.