Suppression of Maternal Lymphocyte Mitogenic Responses by Supernatants From Short‐Term Placental Cell Cultures

ARYE RUBINSTEIN, ZEEV KOREN, R. A. MURPHY

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

ABSTRACT: Human placental cells were freed from lymphocyte contamination on discontinuous BSA gradients. Supernatants from short‐term cultures of these purified placental cell suspensions were predominantly suppressive for maternal lymphocyte blast transformation to phytohemagglutinin and in the mixed lymphocyte culture. The suppressor factor was nondialyzable and did not contain IgG or human chorionic gonadotropin. 1982 Munksgaard

Original languageEnglish (US)
Pages (from-to)260-264
Number of pages5
JournalAmerican Journal of Reproductive Immunology
Volume2
Issue number5
DOIs
StatePublished - Oct 1982

    Fingerprint

Keywords

  • mixed lymphocyte culture
  • phytohemagglutinin
  • Placental cell cultures
  • suppression of maternal immune responses
  • syncytiotrophoblast microvilli

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this