Summary of presentations at the NIH/NIAID new humanized rodent models 2007 workshop

Research output: Contribution to journalArticle

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Abstract

It has long been recognized that a small animal model susceptible to HIV-1 infection with a functional immune system would be extremely useful in the study of HIV/AIDS pathogenesis and for the evaluation of vaccine and therapeutic strategies to combat this disease. By early 2007, a number of reports on various rodent models capable of being infected by and responding to HIV including some with a humanized immune system were published. The New Humanized Rodent Model Workshop, organized by the Division of AIDS (DAIDS), National Institute Allergy and Infection Diseases (NIAID), NIH, was held on September 24, 2007 at Bethesda for the purpose of bringing together key model developers and potential users. This report provides a synopsis of the presentations that discusses the current status of development and use of rodent models to evaluate the pathogenesis of HIV infection and to assess the efficacy of vaccine and therapeutic strategies including microbicides to prevent and/or treat HIVinfection.

Original languageEnglish (US)
Article number3
JournalAIDS Research and Therapy
Volume5
DOIs
StatePublished - Jan 31 2008

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Rodentia
Hypersensitivity
Education
HIV Infections
Immune System
Acquired Immunodeficiency Syndrome
Vaccines
Infection
HIV
Anti-Infective Agents
HIV-1
Animal Models
Therapeutics

ASJC Scopus subject areas

  • Virology
  • Molecular Medicine
  • Pharmacology (medical)

Cite this

Summary of presentations at the NIH/NIAID new humanized rodent models 2007 workshop. / Goldstein, Harris.

In: AIDS Research and Therapy, Vol. 5, 3, 31.01.2008.

Research output: Contribution to journalArticle

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