Abstract
The zona pellucida is a thick extracellular coat that surrounds all mammalian eggs and preimplantation embryos. The zona pellucida supports communication between oocytes and follicle cells during oogenesis; protects oocytes, eggs, and embryos during development, and regulates interactions between ovulated eggs and free-swimming sperm during and following fertilization. Mutant females that produce eggs that lack a zona pellucida are infertile. The functions of the zona pellucida during fertilization now can be ascribed to certain of its glycoproteins. Here we describe some aspects of zona pellucida structure and function as they relate to mammalian fertilization.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 251-258 |
| Number of pages | 8 |
| Journal | Journal of Experimental Zoology |
| Volume | 285 |
| Issue number | 3 |
| DOIs | |
| State | Published - Oct 15 1999 |
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ASJC Scopus subject areas
- Animal Science and Zoology
Cite this
Structure and function of the mammalian egg zona pellucida. / Wassarman, Paul; Chen, Jie; Cohen, Natalie; Litscher, Eveline; Liu, Chengyu; Qi, Huayu; Williams, Zev.
In: Journal of Experimental Zoology, Vol. 285, No. 3, 15.10.1999, p. 251-258.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Structure and function of the mammalian egg zona pellucida
AU - Wassarman, Paul
AU - Chen, Jie
AU - Cohen, Natalie
AU - Litscher, Eveline
AU - Liu, Chengyu
AU - Qi, Huayu
AU - Williams, Zev
PY - 1999/10/15
Y1 - 1999/10/15
N2 - The zona pellucida is a thick extracellular coat that surrounds all mammalian eggs and preimplantation embryos. The zona pellucida supports communication between oocytes and follicle cells during oogenesis; protects oocytes, eggs, and embryos during development, and regulates interactions between ovulated eggs and free-swimming sperm during and following fertilization. Mutant females that produce eggs that lack a zona pellucida are infertile. The functions of the zona pellucida during fertilization now can be ascribed to certain of its glycoproteins. Here we describe some aspects of zona pellucida structure and function as they relate to mammalian fertilization.
AB - The zona pellucida is a thick extracellular coat that surrounds all mammalian eggs and preimplantation embryos. The zona pellucida supports communication between oocytes and follicle cells during oogenesis; protects oocytes, eggs, and embryos during development, and regulates interactions between ovulated eggs and free-swimming sperm during and following fertilization. Mutant females that produce eggs that lack a zona pellucida are infertile. The functions of the zona pellucida during fertilization now can be ascribed to certain of its glycoproteins. Here we describe some aspects of zona pellucida structure and function as they relate to mammalian fertilization.
UR - http://www.scopus.com/inward/record.url?scp=0033569976&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033569976&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1097-010X(19991015)285:3<251::AID-JEZ8>3.0.CO;2-1
DO - 10.1002/(SICI)1097-010X(19991015)285:3<251::AID-JEZ8>3.0.CO;2-1
M3 - Article
C2 - 10497324
AN - SCOPUS:0033569976
VL - 285
SP - 251
EP - 258
JO - Journal of Experimental Zoology
JF - Journal of Experimental Zoology
SN - 0022-104X
IS - 3
ER -