Structure and function of mammalian cilia

Peter Satir, Søren T. Christensen

Research output: Contribution to journalArticle

117 Citations (Scopus)

Abstract

In the past half century, beginning with electron microscopic studies of 9 + 2 motile and 9 + 0 primary cilia, novel insights have been obtained regarding the structure and function of mammalian cilia. All cilia can now be viewed as sensory cellular antennae that coordinate a large number of cellular signaling pathways, sometimes coupling the signaling to ciliary motility or alternatively to cell division and differentiation. This view has had unanticipated consequences for our understanding of developmental processes and human disease.

Original languageEnglish (US)
Pages (from-to)687-693
Number of pages7
JournalHistochemistry and Cell Biology
Volume129
Issue number6
DOIs
StatePublished - Jun 2008

Fingerprint

Cell signaling
cell division
locomotion
Cilia
antennas
Cells
Antennas
Electrons
electrons
Cell Division
Cell Differentiation

Keywords

  • Ciliopathies
  • Motile cilia
  • Motility
  • Primary cilia
  • Sensory organelles
  • Signaling

ASJC Scopus subject areas

  • Cell Biology
  • Instrumentation

Cite this

Structure and function of mammalian cilia. / Satir, Peter; Christensen, Søren T.

In: Histochemistry and Cell Biology, Vol. 129, No. 6, 06.2008, p. 687-693.

Research output: Contribution to journalArticle

Satir, Peter ; Christensen, Søren T. / Structure and function of mammalian cilia. In: Histochemistry and Cell Biology. 2008 ; Vol. 129, No. 6. pp. 687-693.
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