Stoichiometry of aminoacyl-transfer RNA binding and GTP cleavage during chain elongation and translocation

Y. Ono; A. Skoultchi; J. Waterson; P. Lengyel

doi:10.1038/223697a0

Stoichiometry of aminoacyl-transfer RNA binding and GTP cleavage during chain elongation and translocation

Y. Ono, A. Skoultchi, J. Waterson, P. Lengyel

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25 Scopus citations

Abstract

One GTP molecule is cleaved for each aminoacyl-transfer RNA molecule bound to the ribosome during peptide chain elongation. Cleavage of further GTP is needed for translocation.

Original language	English (US)
Pages (from-to)	697-701
Number of pages	5
Journal	Nature
Volume	223
Issue number	5207
DOIs	https://doi.org/10.1038/223697a0
State	Published - 1969
Externally published	Yes

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title = "Stoichiometry of aminoacyl-transfer RNA binding and GTP cleavage during chain elongation and translocation",

abstract = "One GTP molecule is cleaved for each aminoacyl-transfer RNA molecule bound to the ribosome during peptide chain elongation. Cleavage of further GTP is needed for translocation.",

author = "Y. Ono and A. Skoultchi and J. Waterson and P. Lengyel",

year = "1969",

doi = "10.1038/223697a0",

language = "English (US)",

volume = "223",

pages = "697--701",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

number = "5207",

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T1 - Stoichiometry of aminoacyl-transfer RNA binding and GTP cleavage during chain elongation and translocation

AU - Ono, Y.

AU - Skoultchi, A.

AU - Waterson, J.

AU - Lengyel, P.

PY - 1969

Y1 - 1969

N2 - One GTP molecule is cleaved for each aminoacyl-transfer RNA molecule bound to the ribosome during peptide chain elongation. Cleavage of further GTP is needed for translocation.

AB - One GTP molecule is cleaved for each aminoacyl-transfer RNA molecule bound to the ribosome during peptide chain elongation. Cleavage of further GTP is needed for translocation.

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U2 - 10.1038/223697a0

DO - 10.1038/223697a0

M3 - Article

C2 - 5802679

AN - SCOPUS:0014681297

SN - 0028-0836

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SP - 697

EP - 701

JO - Nature

JF - Nature

IS - 5207

ER -

Stoichiometry of aminoacyl-transfer RNA binding and GTP cleavage during chain elongation and translocation

Abstract

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