Abstract
The presentation and treatment of a patient with extra-temporal non-lesional partial epilepsy is discussed herein. His clinical semiology was consistent with supplementary motor area seizures; however, MR imaging did not demonstrate a lesion. A region of stable cortical glucose hypermetabolism in the left frontal region was noted with 2-fluoro-2-deoxy-D-glucose (FDG)-PET. This was consistent with the frequent interictal discharges evident over the left fronto-temporal region and the stereotypic high amplitude ictal discharges arising with highest amplitude from the left frontal region. Epileptiform activity evident on an intracranial 64-point subdural recording grid placed over the left dorsolateral frontal cortex confirmed a distribution concordant with FDG-PET findings. The subsequent resection was guided by the PET and EEG findings rather than structural MR imaging, and a limited cortical resection led to an immediate and substantial reduction in seizure frequency.
Original language | English (US) |
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Pages (from-to) | 1186-1188 |
Number of pages | 3 |
Journal | European Journal of Neurology |
Volume | 14 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2007 |
Externally published | Yes |
Keywords
- Epilepsy surgery
- Epileptogenic zone
- Extra-temporal epilepsy
- Non-lesional epilepsy
- Partial seizure
ASJC Scopus subject areas
- Neurology
- Clinical Neurology