Stereotactic cortical resection in non-lesional extra-temporal partial epilepsy

D. C. Shields, D. J. Costello, J. T. Gale, D. B. Hoch, Emad N. Eskandar

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The presentation and treatment of a patient with extra-temporal non-lesional partial epilepsy is discussed herein. His clinical semiology was consistent with supplementary motor area seizures; however, MR imaging did not demonstrate a lesion. A region of stable cortical glucose hypermetabolism in the left frontal region was noted with 2-fluoro-2-deoxy-D-glucose (FDG)-PET. This was consistent with the frequent interictal discharges evident over the left fronto-temporal region and the stereotypic high amplitude ictal discharges arising with highest amplitude from the left frontal region. Epileptiform activity evident on an intracranial 64-point subdural recording grid placed over the left dorsolateral frontal cortex confirmed a distribution concordant with FDG-PET findings. The subsequent resection was guided by the PET and EEG findings rather than structural MR imaging, and a limited cortical resection led to an immediate and substantial reduction in seizure frequency.

Original languageEnglish (US)
Pages (from-to)1186-1188
Number of pages3
JournalEuropean Journal of Neurology
Volume14
Issue number10
DOIs
StatePublished - Oct 1 2007
Externally publishedYes

Fingerprint

Partial Epilepsy
Seizures
Fluorodeoxyglucose F18
Deoxyglucose
Motor Cortex
Frontal Lobe
Temporal Lobe
Electroencephalography
Stroke
Glucose
Therapeutics

Keywords

  • Epilepsy surgery
  • Epileptogenic zone
  • Extra-temporal epilepsy
  • Non-lesional epilepsy
  • Partial seizure

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Stereotactic cortical resection in non-lesional extra-temporal partial epilepsy. / Shields, D. C.; Costello, D. J.; Gale, J. T.; Hoch, D. B.; Eskandar, Emad N.

In: European Journal of Neurology, Vol. 14, No. 10, 01.10.2007, p. 1186-1188.

Research output: Contribution to journalArticle

Shields, D. C. ; Costello, D. J. ; Gale, J. T. ; Hoch, D. B. ; Eskandar, Emad N. / Stereotactic cortical resection in non-lesional extra-temporal partial epilepsy. In: European Journal of Neurology. 2007 ; Vol. 14, No. 10. pp. 1186-1188.
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