Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series

Some surprising observations regarding their chemical and biological properties

Aaron Balog, Peter Bertinato, Dai Shi Su, Dongfang Meng, Erik Sorensen, Samuel J. Danishefsky, Yu Huang Zheng, Ting Chao Chou, Lifeng He, Susan Band Horwitz

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

Original languageEnglish (US)
Pages (from-to)4529-4532
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number26
DOIs
StatePublished - Jun 30 1997

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series : Some surprising observations regarding their chemical and biological properties. / Balog, Aaron; Bertinato, Peter; Su, Dai Shi; Meng, Dongfang; Sorensen, Erik; Danishefsky, Samuel J.; Zheng, Yu Huang; Chou, Ting Chao; He, Lifeng; Band Horwitz, Susan.

In: Tetrahedron Letters, Vol. 38, No. 26, 30.06.1997, p. 4529-4532.

Research output: Contribution to journalArticle

Balog, Aaron ; Bertinato, Peter ; Su, Dai Shi ; Meng, Dongfang ; Sorensen, Erik ; Danishefsky, Samuel J. ; Zheng, Yu Huang ; Chou, Ting Chao ; He, Lifeng ; Band Horwitz, Susan. / Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series : Some surprising observations regarding their chemical and biological properties. In: Tetrahedron Letters. 1997 ; Vol. 38, No. 26. pp. 4529-4532.
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