SPECT in acute pulmonary embolism

Paul D. Stein; Leonard M. Freeman; H. Dirk Sostman; Lawrence R. Goodman; Pamela K. Woodard; David P. Naidich; Alexander Gottschalk; Dale L. Bailey; Fadi Matta; Abdo Y. Yaekoub; Charles A. Hales; Russell D. Hull; Kenneth V. Leeper; Victor F. Tapson; John G. Weg

doi:10.2967/jnumed.109.063958

SPECT in acute pulmonary embolism

Paul D. Stein, Leonard M. Freeman, H. Dirk Sostman, Lawrence R. Goodman, Pamela K. Woodard, David P. Naidich, Alexander Gottschalk, Dale L. Bailey, Fadi Matta, Abdo Y. Yaekoub, Charles A. Hales, Russell D. Hull, Kenneth V. Leeper, Victor F. Tapson, John G. Weg

Radiology

Research output: Contribution to journal › Review article › peer-review

71 Scopus citations

Abstract

The purpose of this review was to evaluate the accuracy of SPECT in acute pulmonary embolism. Sparse data are available on the accuracy of SPECT based on an objective reference test. Several investigations were reported in which the reference standard for the diagnosis of pulmonary embolism was based in part on the results of SPECT or planar ventilation-perfusion (V/Q) imaging. The sensitivity of SPECT in all but one investigation was at least 90%, and specificity also was generally at least 90%. The sensitivity of SPECT in 4 of 5 investigations was higher than that of planar V/Q imaging. The specificity of SPECT was generally higher, equal, or only somewhat lower than that of planar V/Q imaging. Most investigators reported nondiagnostic SPECT V/Q scans in no more than3%of cases. Methods of obtaining SPECT images, methods of obtaining planar V/Q images, and the criteria for interpretation varied. The general impression is that SPECT is more advantageous than planar V/Q imaging.

Original language	English (US)
Pages (from-to)	1999-2007
Number of pages	9
Journal	Journal of Nuclear Medicine
Volume	50
Issue number	12
DOIs	https://doi.org/10.2967/jnumed.109.063958
State	Published - Dec 1 2009

Keywords

Pulmonary embolism
Pulmonary scintigraphy
SPECT
Technegas
Venous thromboembolic disease
Ventilation-perfusion lung scan

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.2967/jnumed.109.063958

Cite this

@article{1c594d5cffaa45b8ae9ce1c2e9a54f7b,

title = "SPECT in acute pulmonary embolism",

abstract = "The purpose of this review was to evaluate the accuracy of SPECT in acute pulmonary embolism. Sparse data are available on the accuracy of SPECT based on an objective reference test. Several investigations were reported in which the reference standard for the diagnosis of pulmonary embolism was based in part on the results of SPECT or planar ventilation-perfusion (V/Q) imaging. The sensitivity of SPECT in all but one investigation was at least 90%, and specificity also was generally at least 90%. The sensitivity of SPECT in 4 of 5 investigations was higher than that of planar V/Q imaging. The specificity of SPECT was generally higher, equal, or only somewhat lower than that of planar V/Q imaging. Most investigators reported nondiagnostic SPECT V/Q scans in no more than3%of cases. Methods of obtaining SPECT images, methods of obtaining planar V/Q images, and the criteria for interpretation varied. The general impression is that SPECT is more advantageous than planar V/Q imaging.",

keywords = "Pulmonary embolism, Pulmonary scintigraphy, SPECT, Technegas, Venous thromboembolic disease, Ventilation-perfusion lung scan",

author = "Stein, {Paul D.} and Freeman, {Leonard M.} and Sostman, {H. Dirk} and Goodman, {Lawrence R.} and Woodard, {Pamela K.} and Naidich, {David P.} and Alexander Gottschalk and Bailey, {Dale L.} and Fadi Matta and Yaekoub, {Abdo Y.} and Hales, {Charles A.} and Hull, {Russell D.} and Leeper, {Kenneth V.} and Tapson, {Victor F.} and Weg, {John G.}",

year = "2009",

month = dec,

day = "1",

doi = "10.2967/jnumed.109.063958",

language = "English (US)",

volume = "50",

pages = "1999--2007",

journal = "Journal of Nuclear Medicine",

issn = "0161-5505",

publisher = "Society of Nuclear Medicine Inc.",

number = "12",

}

TY - JOUR

T1 - SPECT in acute pulmonary embolism

AU - Stein, Paul D.

AU - Freeman, Leonard M.

AU - Sostman, H. Dirk

AU - Goodman, Lawrence R.

AU - Woodard, Pamela K.

AU - Naidich, David P.

AU - Gottschalk, Alexander

AU - Bailey, Dale L.

AU - Matta, Fadi

AU - Yaekoub, Abdo Y.

AU - Hales, Charles A.

AU - Hull, Russell D.

AU - Leeper, Kenneth V.

AU - Tapson, Victor F.

AU - Weg, John G.

PY - 2009/12/1

Y1 - 2009/12/1

N2 - The purpose of this review was to evaluate the accuracy of SPECT in acute pulmonary embolism. Sparse data are available on the accuracy of SPECT based on an objective reference test. Several investigations were reported in which the reference standard for the diagnosis of pulmonary embolism was based in part on the results of SPECT or planar ventilation-perfusion (V/Q) imaging. The sensitivity of SPECT in all but one investigation was at least 90%, and specificity also was generally at least 90%. The sensitivity of SPECT in 4 of 5 investigations was higher than that of planar V/Q imaging. The specificity of SPECT was generally higher, equal, or only somewhat lower than that of planar V/Q imaging. Most investigators reported nondiagnostic SPECT V/Q scans in no more than3%of cases. Methods of obtaining SPECT images, methods of obtaining planar V/Q images, and the criteria for interpretation varied. The general impression is that SPECT is more advantageous than planar V/Q imaging.

AB - The purpose of this review was to evaluate the accuracy of SPECT in acute pulmonary embolism. Sparse data are available on the accuracy of SPECT based on an objective reference test. Several investigations were reported in which the reference standard for the diagnosis of pulmonary embolism was based in part on the results of SPECT or planar ventilation-perfusion (V/Q) imaging. The sensitivity of SPECT in all but one investigation was at least 90%, and specificity also was generally at least 90%. The sensitivity of SPECT in 4 of 5 investigations was higher than that of planar V/Q imaging. The specificity of SPECT was generally higher, equal, or only somewhat lower than that of planar V/Q imaging. Most investigators reported nondiagnostic SPECT V/Q scans in no more than3%of cases. Methods of obtaining SPECT images, methods of obtaining planar V/Q images, and the criteria for interpretation varied. The general impression is that SPECT is more advantageous than planar V/Q imaging.

KW - Pulmonary embolism

KW - Pulmonary scintigraphy

KW - SPECT

KW - Technegas

KW - Venous thromboembolic disease

KW - Ventilation-perfusion lung scan

UR - http://www.scopus.com/inward/record.url?scp=73349131746&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=73349131746&partnerID=8YFLogxK

U2 - 10.2967/jnumed.109.063958

DO - 10.2967/jnumed.109.063958

M3 - Review article

C2 - 19949025

AN - SCOPUS:73349131746

SN - 0161-5505

VL - 50

SP - 1999

EP - 2007

JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

IS - 12

ER -

SPECT in acute pulmonary embolism

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this