Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

Ronald B. Melles; Jerry A. Schneider; Narsing A. Rao; Barrett Katz

doi:10.1016/0002-9394(87)90171-1

Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

Ronald B. Melles, Jerry A. Schneider, Narsing A. Rao, Barrett Katz

Ophthalmology & Visual Sciences

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.

Original language	English (US)
Pages (from-to)	598-604
Number of pages	7
Journal	American journal of ophthalmology
Volume	104
Issue number	6
DOIs	https://doi.org/10.1016/0002-9394(87)90171-1
State	Published - Dec 1987

ASJC Scopus subject areas

Ophthalmology

Access to Document

10.1016/0002-9394(87)90171-1

Cite this

@article{2a8238423b974d638d5710cf1235aff5,

title = "Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis",

abstract = "We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.",

author = "Melles, {Ronald B.} and Schneider, {Jerry A.} and Rao, {Narsing A.} and Barrett Katz",

year = "1987",

month = dec,

doi = "10.1016/0002-9394(87)90171-1",

language = "English (US)",

volume = "104",

pages = "598--604",

journal = "American Journal of Ophthalmology",

issn = "0002-9394",

publisher = "Elsevier USA",

number = "6",

}

TY - JOUR

T1 - Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

AU - Melles, Ronald B.

AU - Schneider, Jerry A.

AU - Rao, Narsing A.

AU - Katz, Barrett

PY - 1987/12

Y1 - 1987/12

N2 - We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.

AB - We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.

UR - http://www.scopus.com/inward/record.url?scp=0023578529&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023578529&partnerID=8YFLogxK

U2 - 10.1016/0002-9394(87)90171-1

DO - 10.1016/0002-9394(87)90171-1

M3 - Article

C2 - 3688102

AN - SCOPUS:0023578529

SN - 0002-9394

VL - 104

SP - 598

EP - 604

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 6

ER -

Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this