Abstract
Stereoselective approaches to α-trifluoromethylated α-amino acids (α-Tim AAs) have been developed. The stereoconfigurations of the resulting α-Tfm AA precursors were well controlled by using different solvents. The optically active (S)-2-amino-2-phenyl-1,1,1-trifluoropropanoic acid was synthesized by this method.
Original language | English (US) |
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Pages (from-to) | 1379-1381 |
Number of pages | 3 |
Journal | Organic Letters |
Volume | 8 |
Issue number | 7 |
DOIs | |
State | Published - Mar 30 2006 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry