Stereoselective approaches to α-trifluoromethylated α-amino acids (α-Tim AAs) have been developed. The stereoconfigurations of the resulting α-Tfm AA precursors were well controlled by using different solvents. The optically active (S)-2-amino-2-phenyl-1,1,1-trifluoropropanoic acid was synthesized by this method.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Mar 30 2006|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry