Soluble lanthanide salts (LnCl3,·2 LiCl) for the improved addition of organomagnesium reagents to carbonyl compounds

Arkady Krasovskiy; Felix Kopp; Paul Knochel

doi:10.1002/anie.200502485

Soluble lanthanide salts (LnCl₃,·2 LiCl) for the improved addition of organomagnesium reagents to carbonyl compounds

Arkady Krasovskiy, Felix Kopp, Paul Knochel

Research output: Contribution to journal › Article › peer-review

268 Scopus citations

Abstract

(Chemical Equation Presented) Easy-to-prepare solutions of LnCl ₃·2 LiCl (Ln = La, Ce, Nd) (0.3-0.5 M in THF) are a unique source of soluble lanthanide salts with versatile applications in organic synthesis. These salts can serve as promoters or catalysts for the addition of organometallic compounds to sterically hindered, enolizable or α,β-unsaturated ketones or imines.

Original language	English (US)
Pages (from-to)	497-500
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	3
DOIs	https://doi.org/10.1002/anie.200502485
State	Published - Jan 9 2006
Externally published	Yes

Keywords

1,2-additions
Enols
Grignard reaction
Imines
Lanthanides

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1002/anie.200502485

Cite this

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abstract = "(Chemical Equation Presented) Easy-to-prepare solutions of LnCl 3·2 LiCl (Ln = La, Ce, Nd) (0.3-0.5 M in THF) are a unique source of soluble lanthanide salts with versatile applications in organic synthesis. These salts can serve as promoters or catalysts for the addition of organometallic compounds to sterically hindered, enolizable or α,β-unsaturated ketones or imines.",

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KW - Grignard reaction

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KW - Lanthanides

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