Small-animal research imaging devices

Eugene J. Fine, Lawrence H. Herbst, Linda A. Jelicks, Wade R. Koba, Daniel Theele

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The scientific study of living animals may be dated to Aristotle's original dissections, but modern animal studies are perhaps a century in the making, and advanced animal imaging has emerged only during the past few decades. In vivo imaging now occupies a growing role in the scientific research paradigm. Imaging of small animals has been particularly useful to help understand human molecular biology and pathophysiology using rodents, especially using genetically engineered mice (GEM) with spontaneous diseases that closely mimic human diseases. Specific examples of GEM models of veterinary diseases exist, but in general, GEM for veterinary research has lagged behind human research applications. However, the development of spontaneous disease models from GEM may also hold potential for veterinary research. The imaging techniques most widely used in small-animal research are CT, PET, single-photon emission CT, MRI, and optical fluorescent and luminescent imaging.

Original languageEnglish (US)
Pages (from-to)57-65
Number of pages9
JournalSeminars in Nuclear Medicine
Volume44
Issue number1
DOIs
StatePublished - Jan 2014

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Equipment and Supplies
Research
Photons
Dissection
Molecular Biology
Rodentia
Positron Emission Tomography Computed Tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Small-animal research imaging devices. / Fine, Eugene J.; Herbst, Lawrence H.; Jelicks, Linda A.; Koba, Wade R.; Theele, Daniel.

In: Seminars in Nuclear Medicine, Vol. 44, No. 1, 01.2014, p. 57-65.

Research output: Contribution to journalArticle

Fine, Eugene J. ; Herbst, Lawrence H. ; Jelicks, Linda A. ; Koba, Wade R. ; Theele, Daniel. / Small-animal research imaging devices. In: Seminars in Nuclear Medicine. 2014 ; Vol. 44, No. 1. pp. 57-65.
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