Slowed saccades in the acquired immunodeficiency syndrome

Ngoc Nguyen; Steve Rimmer; Barrett Katz

doi:10.1016/0002-9394(89)90658-2

Slowed saccades in the acquired immunodeficiency syndrome

Ngoc Nguyen, Steve Rimmer, Barrett Katz

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We recorded eye movements using infrared oculography in ten patients with the acquired immunodeficiency syndrome (AIDS) and ten control subjects of similar age. Peak saccadic velocity for the AIDS group was significantly lower than that of the control group for both adducting and abducting saccades (P < .001). Saccadic duration for the AIDS group was significantly greater than that of the controls for both adducting and abducting saccades (P < .02 for adduction and P < .01 for abduction). There was no difference in saccadic latencies between the two groups. We add slowed saccades to the ocular motility manifestations of AIDS. Our study indicated that analysis of ocular motility may be of value in providing early detection of neurologic dysfunction, and may also be an important quantitative measure of the responsiveness of patients to different types of potential therapies.

Original language	English (US)
Pages (from-to)	356-360
Number of pages	5
Journal	American journal of ophthalmology
Volume	107
Issue number	4
DOIs	https://doi.org/10.1016/0002-9394(89)90658-2
State	Published - Apr 15 1989
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0002-9394(89)90658-2

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abstract = "We recorded eye movements using infrared oculography in ten patients with the acquired immunodeficiency syndrome (AIDS) and ten control subjects of similar age. Peak saccadic velocity for the AIDS group was significantly lower than that of the control group for both adducting and abducting saccades (P < .001). Saccadic duration for the AIDS group was significantly greater than that of the controls for both adducting and abducting saccades (P < .02 for adduction and P < .01 for abduction). There was no difference in saccadic latencies between the two groups. We add slowed saccades to the ocular motility manifestations of AIDS. Our study indicated that analysis of ocular motility may be of value in providing early detection of neurologic dysfunction, and may also be an important quantitative measure of the responsiveness of patients to different types of potential therapies.",

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AU - Katz, Barrett

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AB - We recorded eye movements using infrared oculography in ten patients with the acquired immunodeficiency syndrome (AIDS) and ten control subjects of similar age. Peak saccadic velocity for the AIDS group was significantly lower than that of the control group for both adducting and abducting saccades (P < .001). Saccadic duration for the AIDS group was significantly greater than that of the controls for both adducting and abducting saccades (P < .02 for adduction and P < .01 for abduction). There was no difference in saccadic latencies between the two groups. We add slowed saccades to the ocular motility manifestations of AIDS. Our study indicated that analysis of ocular motility may be of value in providing early detection of neurologic dysfunction, and may also be an important quantitative measure of the responsiveness of patients to different types of potential therapies.

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Slowed saccades in the acquired immunodeficiency syndrome

Abstract

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UN SDGs

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