Sheehan's syndrome followed by successful pregnancy. A case report

Sheehan's syndrome is a complication of pregnancy rarely encountered in modern obstetric practice. The management of this condition involves substitution therapy of the hormones produced by the various endocrine glands under hypothalamic and pituitary control. There have been few reports on the occurrence of spontaneous pregnancy in patients with Sheehan's syndrome. This paper describes the investigation and management of a patient with longstanding panhypopituitarism. Hormone replacement therapy, and specifically induction of ovulation with human menopausal gonadotrophins, resulted in a successful outcome of pregnancy.