Sensitivity of myoma imaging using laparoscopic ultrasound compared with magnetic resonance imaging and transvaginal ultrasound

David J. Levine, Jay M. Berman, Micah Harris, Scott G. Chudnoff, Fredrick S. Whaley, Suzanne L. Palmer

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Study Objective: To determine the efficacy of laparoscopic ultrasound (LUS) as compared with contrast-enhanced magnetic resonance imaging (CE-MRI) and transvaginal ultrasound (TVUS) in detection of uterine myomas. Design: Retrospective study of imaging methods used in a trial of LUS-guided radiofrequency volumetric thermal ablation in women with symptomatic myomas (Canadian Task Force classification II-2). Setting: Eleven medical university or private outpatient surgery clinics in the United States (nine sites) and Latin America (two sites). Patients: One hundred thirty-five women with symptomatic myomas and objectively confirmed moderate to severe heavy menstrual bleeding. Interventions: LUS-guided radiofrequency volumetric thermal ablation of myomas. Measurements and Main Results: Preoperative TVUS scans and CE-MRIs were read at each site, and all CE-MRIs were read by a central reader. LUS-guided scans were obtained intraoperatively by each surgeon by mapping the uterus just before radiofrequency volumetric thermal ablation. The imaging methods and their yields in terms of number of myomas found per subject were as follows: TVUS, 403 myomas (mean [SD] 3 [1.8]; range, 1-8); site CE-MRI, 562 myomas (4.2 [3.8]; range, 1-18); central reader, 619 myomas (4.6 [3.7]; range, 0-20); and LUS, 818 myomas (6.1 [4.9]; range, 1-29) (p < .001). LUS was superior to TVUS, CE-MRI, and the central reader for detection of small (≤1 cm3) myomas. Most imaged myomas were intramural: 197 (50.9%) by TVUS, 298 (55.5%) by site CE-MRI, 290 (48.7%) by the central reader, and 386 (48.5%) by LUS. Conclusion: Compared with CE-MRI and TVUS, LUS demonstrates the most myomas, regardless of size or type.

Original languageEnglish (US)
Pages (from-to)770-774
Number of pages5
JournalJournal of Minimally Invasive Gynecology
Volume20
Issue number6
DOIs
StatePublished - 2013

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Myoma
Magnetic Resonance Imaging
Hot Temperature
Latin America
Advisory Committees
Ambulatory Care Facilities
Ambulatory Surgical Procedures
Uterus
Retrospective Studies

Keywords

  • Intraabdominal ultrasound
  • Laparoscopic ultrasound
  • Magnetic resonance imaging
  • Myoma
  • Radiofrequency volumetric thermal ablation
  • Transvaginal ultrasound

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Sensitivity of myoma imaging using laparoscopic ultrasound compared with magnetic resonance imaging and transvaginal ultrasound. / Levine, David J.; Berman, Jay M.; Harris, Micah; Chudnoff, Scott G.; Whaley, Fredrick S.; Palmer, Suzanne L.

In: Journal of Minimally Invasive Gynecology, Vol. 20, No. 6, 2013, p. 770-774.

Research output: Contribution to journalArticle

Levine, David J. ; Berman, Jay M. ; Harris, Micah ; Chudnoff, Scott G. ; Whaley, Fredrick S. ; Palmer, Suzanne L. / Sensitivity of myoma imaging using laparoscopic ultrasound compared with magnetic resonance imaging and transvaginal ultrasound. In: Journal of Minimally Invasive Gynecology. 2013 ; Vol. 20, No. 6. pp. 770-774.
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abstract = "Study Objective: To determine the efficacy of laparoscopic ultrasound (LUS) as compared with contrast-enhanced magnetic resonance imaging (CE-MRI) and transvaginal ultrasound (TVUS) in detection of uterine myomas. Design: Retrospective study of imaging methods used in a trial of LUS-guided radiofrequency volumetric thermal ablation in women with symptomatic myomas (Canadian Task Force classification II-2). Setting: Eleven medical university or private outpatient surgery clinics in the United States (nine sites) and Latin America (two sites). Patients: One hundred thirty-five women with symptomatic myomas and objectively confirmed moderate to severe heavy menstrual bleeding. Interventions: LUS-guided radiofrequency volumetric thermal ablation of myomas. Measurements and Main Results: Preoperative TVUS scans and CE-MRIs were read at each site, and all CE-MRIs were read by a central reader. LUS-guided scans were obtained intraoperatively by each surgeon by mapping the uterus just before radiofrequency volumetric thermal ablation. The imaging methods and their yields in terms of number of myomas found per subject were as follows: TVUS, 403 myomas (mean [SD] 3 [1.8]; range, 1-8); site CE-MRI, 562 myomas (4.2 [3.8]; range, 1-18); central reader, 619 myomas (4.6 [3.7]; range, 0-20); and LUS, 818 myomas (6.1 [4.9]; range, 1-29) (p < .001). LUS was superior to TVUS, CE-MRI, and the central reader for detection of small (≤1 cm3) myomas. Most imaged myomas were intramural: 197 (50.9{\%}) by TVUS, 298 (55.5{\%}) by site CE-MRI, 290 (48.7{\%}) by the central reader, and 386 (48.5{\%}) by LUS. Conclusion: Compared with CE-MRI and TVUS, LUS demonstrates the most myomas, regardless of size or type.",
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AU - Levine, David J.

AU - Berman, Jay M.

AU - Harris, Micah

AU - Chudnoff, Scott G.

AU - Whaley, Fredrick S.

AU - Palmer, Suzanne L.

PY - 2013

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N2 - Study Objective: To determine the efficacy of laparoscopic ultrasound (LUS) as compared with contrast-enhanced magnetic resonance imaging (CE-MRI) and transvaginal ultrasound (TVUS) in detection of uterine myomas. Design: Retrospective study of imaging methods used in a trial of LUS-guided radiofrequency volumetric thermal ablation in women with symptomatic myomas (Canadian Task Force classification II-2). Setting: Eleven medical university or private outpatient surgery clinics in the United States (nine sites) and Latin America (two sites). Patients: One hundred thirty-five women with symptomatic myomas and objectively confirmed moderate to severe heavy menstrual bleeding. Interventions: LUS-guided radiofrequency volumetric thermal ablation of myomas. Measurements and Main Results: Preoperative TVUS scans and CE-MRIs were read at each site, and all CE-MRIs were read by a central reader. LUS-guided scans were obtained intraoperatively by each surgeon by mapping the uterus just before radiofrequency volumetric thermal ablation. The imaging methods and their yields in terms of number of myomas found per subject were as follows: TVUS, 403 myomas (mean [SD] 3 [1.8]; range, 1-8); site CE-MRI, 562 myomas (4.2 [3.8]; range, 1-18); central reader, 619 myomas (4.6 [3.7]; range, 0-20); and LUS, 818 myomas (6.1 [4.9]; range, 1-29) (p < .001). LUS was superior to TVUS, CE-MRI, and the central reader for detection of small (≤1 cm3) myomas. Most imaged myomas were intramural: 197 (50.9%) by TVUS, 298 (55.5%) by site CE-MRI, 290 (48.7%) by the central reader, and 386 (48.5%) by LUS. Conclusion: Compared with CE-MRI and TVUS, LUS demonstrates the most myomas, regardless of size or type.

AB - Study Objective: To determine the efficacy of laparoscopic ultrasound (LUS) as compared with contrast-enhanced magnetic resonance imaging (CE-MRI) and transvaginal ultrasound (TVUS) in detection of uterine myomas. Design: Retrospective study of imaging methods used in a trial of LUS-guided radiofrequency volumetric thermal ablation in women with symptomatic myomas (Canadian Task Force classification II-2). Setting: Eleven medical university or private outpatient surgery clinics in the United States (nine sites) and Latin America (two sites). Patients: One hundred thirty-five women with symptomatic myomas and objectively confirmed moderate to severe heavy menstrual bleeding. Interventions: LUS-guided radiofrequency volumetric thermal ablation of myomas. Measurements and Main Results: Preoperative TVUS scans and CE-MRIs were read at each site, and all CE-MRIs were read by a central reader. LUS-guided scans were obtained intraoperatively by each surgeon by mapping the uterus just before radiofrequency volumetric thermal ablation. The imaging methods and their yields in terms of number of myomas found per subject were as follows: TVUS, 403 myomas (mean [SD] 3 [1.8]; range, 1-8); site CE-MRI, 562 myomas (4.2 [3.8]; range, 1-18); central reader, 619 myomas (4.6 [3.7]; range, 0-20); and LUS, 818 myomas (6.1 [4.9]; range, 1-29) (p < .001). LUS was superior to TVUS, CE-MRI, and the central reader for detection of small (≤1 cm3) myomas. Most imaged myomas were intramural: 197 (50.9%) by TVUS, 298 (55.5%) by site CE-MRI, 290 (48.7%) by the central reader, and 386 (48.5%) by LUS. Conclusion: Compared with CE-MRI and TVUS, LUS demonstrates the most myomas, regardless of size or type.

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KW - Myoma

KW - Radiofrequency volumetric thermal ablation

KW - Transvaginal ultrasound

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