TY - JOUR
T1 - Scleritis as the Presenting Manifestation of Procainamide-induced Lupus
AU - Turgeon, Paul W.
AU - Slamovits, Thomas L.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Scleritis developed in a patient using procainamide as part of a druginduced lupus syndrome. Systemic findings, which developed after the onset of ocular signs and symptoms, included arthralgias, myalgias, weight loss, and markedly elevated antinuclear antibody (ANA) titers and antihistone titers. The clinical picture and laboratory abnormalities improved after discontinuation of the drug. Although systemic findings secondary to drug-induced lupus have been well described in the medical literature, this case represents the first detailed ophthalmologic documentation of scleritis as the presenting manifestation of procainamide-induced lupus.
AB - Scleritis developed in a patient using procainamide as part of a druginduced lupus syndrome. Systemic findings, which developed after the onset of ocular signs and symptoms, included arthralgias, myalgias, weight loss, and markedly elevated antinuclear antibody (ANA) titers and antihistone titers. The clinical picture and laboratory abnormalities improved after discontinuation of the drug. Although systemic findings secondary to drug-induced lupus have been well described in the medical literature, this case represents the first detailed ophthalmologic documentation of scleritis as the presenting manifestation of procainamide-induced lupus.
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U2 - 10.1016/S0161-6420(89)32941-1
DO - 10.1016/S0161-6420(89)32941-1
M3 - Article
C2 - 2645552
AN - SCOPUS:0024562141
SN - 0161-6420
VL - 96
SP - 68
EP - 71
JO - Ophthalmology
JF - Ophthalmology
IS - 1
ER -