TY - JOUR
T1 - Role of elevated cancer antigen 19-9 in women with mature cystic teratoma
AU - Frimer, Marina
AU - Seagle, Brandon Luke L.
AU - Chudnoff, Scott
AU - Goldberg, Gary L.
AU - Shahabi, Shohreh
N1 - Publisher Copyright:
© The Author(s) 2014.
PY - 2014/10/11
Y1 - 2014/10/11
N2 - The objective of this study was to determine how often an elevated cancer antigen (CA) 19-9 (≥ 37 U/mL) was present during the preoperative evaluation of women with a mature cystic teratoma (MCT). This was a retrospective, consecutive case series (N = 139) of histologically proven MCT treated at Montefiore Medical Center from 1997 to 2008. Data were analyzed for patient and tumor characteristics, tumor markers (CA 19-9, CA 125, and carcinoembryonic antigen [CEA]), preoperative imaging, and procedure. CA 19-9 was elevated in 37.4% of patients. Elevated CA 19-9 was not significantly associated with age, race, CA 125 (≥35 U/mL), CEA (≥5 ng/mL), MCT size, or the presence of bilateral MCTs. Of the patients, 59% were ≥40 years old. Age <40 years was associated with cystectomy rather than oophorectomy (P <.001), regardless of CA 19-9 (P =.09). Elevated preoperative CA 19-9 in patients with MCT was associated with increased preoperative computed tomography (P =.04).
AB - The objective of this study was to determine how often an elevated cancer antigen (CA) 19-9 (≥ 37 U/mL) was present during the preoperative evaluation of women with a mature cystic teratoma (MCT). This was a retrospective, consecutive case series (N = 139) of histologically proven MCT treated at Montefiore Medical Center from 1997 to 2008. Data were analyzed for patient and tumor characteristics, tumor markers (CA 19-9, CA 125, and carcinoembryonic antigen [CEA]), preoperative imaging, and procedure. CA 19-9 was elevated in 37.4% of patients. Elevated CA 19-9 was not significantly associated with age, race, CA 125 (≥35 U/mL), CEA (≥5 ng/mL), MCT size, or the presence of bilateral MCTs. Of the patients, 59% were ≥40 years old. Age <40 years was associated with cystectomy rather than oophorectomy (P <.001), regardless of CA 19-9 (P =.09). Elevated preoperative CA 19-9 in patients with MCT was associated with increased preoperative computed tomography (P =.04).
KW - CA 19-9
KW - adnexal mass
KW - ovarian tumor
KW - teratoma
KW - tumor marker
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U2 - 10.1177/1933719114525274
DO - 10.1177/1933719114525274
M3 - Article
C2 - 24577158
AN - SCOPUS:84908888224
SN - 1933-7191
VL - 21
SP - 1307
EP - 1311
JO - Reproductive Sciences
JF - Reproductive Sciences
IS - 10
ER -
