Risk factors for spinal cord injury during surgery for spinal deformity

Michael G. Vitale, Derek W. Moore, Hiroko Matsumoto, Ronald G. Emerson, Whitney A. Booker, Jaime A. Gomez, Edward J. Gallo, Joshua E. Hyman, David P. Roye

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Background: Spinal cord monitoring is now considered standard care during surgery for spinal deformity. Combined somatosensory and motor evoked potential monitoring allows the detection of early spinal cord dysfunction in most patients. The purpose of the current study was to identify clinical factors that increase the risk of intraoperative electrophysical changes and to provide management recommendations. Methods: The records of 162 consecutive patients who underwent surgery for the treatment of spinal deformity at a tertiary referral center were reviewed. Electrophysical monitoring of these patients was considered to have been successful if reproducible signals had been obtained. Relevant electrophysical changes included a reduction, as compared with baseline, of >50% in the amplitude of the somatosensory evoked potentials; an increase, as compared with baseline, of >10% in the latency of the somatosensory evoked potentials; a loss of motor evoked potentials; and an abrupt decrease of >75% in the motor evoked potentials. Results: One hundred and fifty-one (93%) of the 162 patients were monitored successfully. Four of the eleven patients with unsuccessful monitoring had neuromuscular scoliosis. Twelve of the 151 successfully monitored patients had a true electrophysical event, and two of them were found to have new postoperative neurologic deficits that represented a change from the findings of their preoperative neurologic examination. The determined causes of these electrophysical events included curve correction in eight patients, hypotension in two, direct cord trauma in one, and malposition of a pedicle screw in one. The patients with a true electrophysical event had a significantly higher rate of neurologic events than did the patients who did not have a true electrophysical event (p <0.001). The rate of true electrophysical events was significantly higher in the patients with cardiopulmonary comorbidities than it was in the patients with no comorbidities (p = 0.011). Conclusions: Combined somatosensory and motor evoked potential monitoring effectively prevents neurologic injury in most children undergoing surgery for spinal deformity. Despite the potential for false-positive results, we recommend setting a low threshold for defining relevant electrophysical changes. Rapid intervention can reverse these changes and avoid potentially serious neurologic complications. Patients with cardiopulmonary comorbidities may be at a higher risk for having relevant electrophysical events. Level of Evidence: Diagnostic Level III. See Instructions to Authors for a complete description of levels of evidence.

Original languageEnglish (US)
Pages (from-to)64-71
Number of pages8
JournalJournal of Bone and Joint Surgery - Series A
Volume92
Issue number1
DOIs
StatePublished - Jan 1 2010
Externally publishedYes

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Spinal Cord Injuries
Motor Evoked Potentials
Somatosensory Evoked Potentials
Comorbidity
Nervous System
Spinal Cord
Neuromuscular Monitoring
Nervous System Trauma
Neurologic Examination
Physiologic Monitoring
Scoliosis
Neurologic Manifestations
Tertiary Care Centers
Hypotension
Wounds and Injuries

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Vitale, M. G., Moore, D. W., Matsumoto, H., Emerson, R. G., Booker, W. A., Gomez, J. A., ... Roye, D. P. (2010). Risk factors for spinal cord injury during surgery for spinal deformity. Journal of Bone and Joint Surgery - Series A, 92(1), 64-71. https://doi.org/10.2106/JBJS.H.01839

Risk factors for spinal cord injury during surgery for spinal deformity. / Vitale, Michael G.; Moore, Derek W.; Matsumoto, Hiroko; Emerson, Ronald G.; Booker, Whitney A.; Gomez, Jaime A.; Gallo, Edward J.; Hyman, Joshua E.; Roye, David P.

In: Journal of Bone and Joint Surgery - Series A, Vol. 92, No. 1, 01.01.2010, p. 64-71.

Research output: Contribution to journalArticle

Vitale, MG, Moore, DW, Matsumoto, H, Emerson, RG, Booker, WA, Gomez, JA, Gallo, EJ, Hyman, JE & Roye, DP 2010, 'Risk factors for spinal cord injury during surgery for spinal deformity', Journal of Bone and Joint Surgery - Series A, vol. 92, no. 1, pp. 64-71. https://doi.org/10.2106/JBJS.H.01839
Vitale, Michael G. ; Moore, Derek W. ; Matsumoto, Hiroko ; Emerson, Ronald G. ; Booker, Whitney A. ; Gomez, Jaime A. ; Gallo, Edward J. ; Hyman, Joshua E. ; Roye, David P. / Risk factors for spinal cord injury during surgery for spinal deformity. In: Journal of Bone and Joint Surgery - Series A. 2010 ; Vol. 92, No. 1. pp. 64-71.
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