TY - JOUR
T1 - Risk, coping and PTSD symptom trajectories in World Trade Center responders
AU - Feder, Adriana
AU - Mota, Natalie
AU - Salim, Ryan
AU - Rodriguez, Janice
AU - Singh, Ritika
AU - Schaffer, Jamie
AU - Schechter, Clyde B.
AU - Cancelmo, Leo M.
AU - Bromet, Evelyn J.
AU - Katz, Craig L.
AU - Reissman, Dori B.
AU - Ozbay, Fatih
AU - Kotov, Roman
AU - Crane, Michael
AU - Harrison, Denise J.
AU - Herbert, Robin
AU - Levin, Stephen M.
AU - Luft, Benjamin J.
AU - Moline, Jacqueline M.
AU - Stellman, Jeanne M.
AU - Udasin, Iris G.
AU - Landrigan, Philip J.
AU - Zvolensky, Michael J.
AU - Yehuda, Rachel
AU - Southwick, Steven M.
AU - Pietrzak, Robert H.
N1 - Funding Information:
This work was supported by the CDC/ National Institute for Occupational Safety and Health (NIOSH) (A.F., R.H.P. and S.M.S., research contract # 200-2011-41919 ). The CDC/NIOSH did not contribute to study design; data collection, analysis or interpretation; writing of the report; or decision to submit the manuscript for publication.
Funding Information:
Dr. Feder (co-inventor) and Mount Sinai have been named on a use patent application of ketamine for the treatment of posttraumatic stress disorder; patent is currently pending. Dr. Schechter has received consulting fees from Accolade, Inc., for analysis of claims data in evaluation of the effectiveness of their services and for technical support provided to in-house statistical staff. Dr. Crane has received funding from the CDC/NIOSH WTC Health Program contract # 200-2011-39356. Dr. Yehuda has a patent entitled Genes Associated with Posttraumatic Stress Disorder (2012/0039, 812). Dr. Southwick has received royalties from two books published by Cambridge University Press: Resilience: The Science of Mastering Life’s Greatest Challenges and Resilience and Mental Health: Challenges Across the Lifespan. Dr. Pietrzak is a scientific consultant to CogState Ltd. Drs. Mota, Salim, Bromet, Katz, Reissman, Ozbay, Kotov, Harrison, Herbert, Levin, Luft, Moline, Stellman, Udasin, Landrigan, Zvolensky and Pietrzak, and Ms. Rodriguez, Ms. Singh, Ms. Schaffer and Mr. Cancelmo report no competing interests.
Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Trajectories of disaster-related posttraumatic stress disorder (PTSD) symptoms are often heterogeneous, and associated with common and unique risk factors, yet little is known about potentially modifiable psychosocial characteristics associated with low-symptom and recovering trajectories in disaster responders. A total of 4487 rescue and recovery workers (1874 police and 2613 non-traditional responders) involved during and in the aftermath of the unprecedented World Trade Center (WTC) attacks, were assessed an average of 3, 6, 8, and 12 years post-9/11/2001. Among police responders, WTC-related PTSD symptoms were characterized by four trajectories, including no/low-symptom (76.1%), worsening (12.1%), improving (7.5%), and chronic (4.4%) trajectories. In non-traditional responders, a five-trajectory solution was optimal, with fewer responders in a no/low-symptom trajectory (55.5%), and the remainder in subtly worsening (19.3%), chronic (10.8%), improving (8.5%), and steeply worsening (5.9%) trajectories. Consistent factors associated with symptomatic PTSD trajectories across responder groups included Hispanic ethnicity, pre-9/11 psychiatric history, greater WTC exposure, greater medical illness burden, life stressors and post-9/11 traumas, and maladaptive coping (e.g., substance use, avoidance coping). Higher perceived preparedness, greater sense of purpose in life, and positive emotion-focused coping (e.g., positive reframing, acceptance) were negatively associated with symptomatic trajectories. Findings in this unique cohort indicate considerable heterogeneity in WTC-related PTSD symptom trajectories over 12 years post-9/11/2001, with lower rates of elevated PTSD symptoms in police than in non-traditional responders. They further provide a comprehensive risk prediction model of PTSD symptom trajectories, which can inform prevention, monitoring, and treatment efforts in WTC and other disaster responders.
AB - Trajectories of disaster-related posttraumatic stress disorder (PTSD) symptoms are often heterogeneous, and associated with common and unique risk factors, yet little is known about potentially modifiable psychosocial characteristics associated with low-symptom and recovering trajectories in disaster responders. A total of 4487 rescue and recovery workers (1874 police and 2613 non-traditional responders) involved during and in the aftermath of the unprecedented World Trade Center (WTC) attacks, were assessed an average of 3, 6, 8, and 12 years post-9/11/2001. Among police responders, WTC-related PTSD symptoms were characterized by four trajectories, including no/low-symptom (76.1%), worsening (12.1%), improving (7.5%), and chronic (4.4%) trajectories. In non-traditional responders, a five-trajectory solution was optimal, with fewer responders in a no/low-symptom trajectory (55.5%), and the remainder in subtly worsening (19.3%), chronic (10.8%), improving (8.5%), and steeply worsening (5.9%) trajectories. Consistent factors associated with symptomatic PTSD trajectories across responder groups included Hispanic ethnicity, pre-9/11 psychiatric history, greater WTC exposure, greater medical illness burden, life stressors and post-9/11 traumas, and maladaptive coping (e.g., substance use, avoidance coping). Higher perceived preparedness, greater sense of purpose in life, and positive emotion-focused coping (e.g., positive reframing, acceptance) were negatively associated with symptomatic trajectories. Findings in this unique cohort indicate considerable heterogeneity in WTC-related PTSD symptom trajectories over 12 years post-9/11/2001, with lower rates of elevated PTSD symptoms in police than in non-traditional responders. They further provide a comprehensive risk prediction model of PTSD symptom trajectories, which can inform prevention, monitoring, and treatment efforts in WTC and other disaster responders.
KW - Coping
KW - Posttraumatic stress disorder
KW - Responders
KW - Risk
KW - Trajectories
KW - World Trade Center
UR - http://www.scopus.com/inward/record.url?scp=84979586829&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84979586829&partnerID=8YFLogxK
U2 - 10.1016/j.jpsychires.2016.07.003
DO - 10.1016/j.jpsychires.2016.07.003
M3 - Article
C2 - 27468166
AN - SCOPUS:84979586829
SN - 0022-3956
VL - 82
SP - 68
EP - 79
JO - Journal of Psychiatric Research
JF - Journal of Psychiatric Research
ER -