Reversible and irreversible ototoxicity has been documented following the administration of various therapeutic agents. Reversible hearing loss is a known complication folio wing the administration of quinine, salicylates and other nonsteroidal anti-inflammatory drugs, and erythromycin. We report a case of reversible hearing loss following OKT3 (murine monoclonal antibody CD3) administration. OKT3, a monoclonal antibody used as an immunosuppressant following cadaveric renal transplants, was associated with a transient sensorineural hearing loss that reversed following discontinuation of OKT3.
|Original language||English (US)|
|Number of pages||3|
|Journal||Annals of Otology, Rhinology and Laryngology|
|Publication status||Published - Sep 3 1997|
- Sensorineural hearing loss
ASJC Scopus subject areas