TY - JOUR
T1 - Respiratory symptoms were associated with lower spirometry results during the first examination of WTC responders
AU - Udasin, Iris
AU - Schechter, Clyde
AU - Crowley, Laura
AU - Sotolongo, Anays
AU - Gochfeld, Michael
AU - Luft, Benjamin
AU - Moline, Jacqueline
AU - Harrison, Denise
AU - Enright, Paul
N1 - Funding Information:
This work was supported by the Centers for Disease Control and NIOSH, contract 200–2002-0038 and grant 5U1O 0H008232 . Its contents are solely the responsibility of the authors and do not necessarily represent the official views of NIOSH.
PY - 2011/1
Y1 - 2011/1
N2 - Objective: Determine if World Trade Center (WTC) disaster responders had lower lung function and higher bronchodilator responsiveness than those with respiratory symptoms and conditions. Methods: We evaluated cardinal respiratory symptoms (dyspnea, wheezing, dry cough, productive cough) and determined the difference in FEV1, FVC, and bronchodilator responsiveness. Results: All respiratory symptoms were associated with a lower FEV1 and FVC, and a larger bronchodilator response. Responders reporting chronic productive cough, starting during WTC work and persisting, had a mean FEV1 109 mL lower than those without chronic persistent cough; their odds of having abnormally low FEV1 was 1.40 times higher; and they were 1.65 times as likely to demonstrate bronchodilator responsiveness. Conclusions:: Responders reporting chronic persistent cough, wheezing or dyspnea at first medical examination were more likely to have lower lung function and bronchodilator responsiveness.
AB - Objective: Determine if World Trade Center (WTC) disaster responders had lower lung function and higher bronchodilator responsiveness than those with respiratory symptoms and conditions. Methods: We evaluated cardinal respiratory symptoms (dyspnea, wheezing, dry cough, productive cough) and determined the difference in FEV1, FVC, and bronchodilator responsiveness. Results: All respiratory symptoms were associated with a lower FEV1 and FVC, and a larger bronchodilator response. Responders reporting chronic productive cough, starting during WTC work and persisting, had a mean FEV1 109 mL lower than those without chronic persistent cough; their odds of having abnormally low FEV1 was 1.40 times higher; and they were 1.65 times as likely to demonstrate bronchodilator responsiveness. Conclusions:: Responders reporting chronic persistent cough, wheezing or dyspnea at first medical examination were more likely to have lower lung function and bronchodilator responsiveness.
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U2 - 10.1097/JOM.0b013e3182028e5c
DO - 10.1097/JOM.0b013e3182028e5c
M3 - Article
C2 - 21187790
AN - SCOPUS:78751642728
SN - 1076-2752
VL - 53
SP - 49
EP - 54
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
IS - 1
ER -
