Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110α and are disrupted in oncogenic p85 mutants

Haiyan Wu, S. Chandra Shekar, Rory J. Flinn, Mirvat El-Sibai, Bijay S. Jaiswal, K. Ilker Sen, Vasantharajan Janakiraman, Somasekar Seshagiri, Gary J. Gerfen, Mark E. Girvin, Jonathan M. Backer

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