Abstract
Sixty three Caucasian patients with either melanoma, keratoacanthoma or squamous cell carcinoma were human leucocyte antigen (HLA) typed. The regressing tumour groups were compared with their non-regressing counterparts, and the patient groups were compared with a control Caucasian population. Melanoma patients showing histological regression were more likely to be HLA-B22 positive, and HLA-B27 and -DR1 negative, than those without features of regression. When compared with a control population, the group of melanoma patients were more likely to be HLA-B22 positive. Comparison of the group of keratoacanthomas, a self-regressing tumour, and the group of squamous cell carcinomas, a non-regressing tumour, did not show any significant differences in HLA typing.
Original language | English (US) |
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Pages (from-to) | 539-544 |
Number of pages | 6 |
Journal | Melanoma Research |
Volume | 9 |
Issue number | 6 |
DOIs | |
State | Published - 1999 |
Externally published | Yes |
Keywords
- HLA-B22
- HLA-B27
- HLA-DR1
- Skin cancer
- Tumour regression
ASJC Scopus subject areas
- Oncology
- Dermatology
- Cancer Research