Refractory obsessive-compulsive disorder: State-of-the-art treatment

Eric Hollander, Carol A. Bienstock, Lorrin M. Koran, Stefano Pallanti, Donatella Marazziti, Steven A. Rasmussen, Luigi Ravizza, Chawkie Benkelfat, Sanjaya Saxena, Benjamin D. Greenberg, Yehuda Sasson, Joseph Zohar

Research output: Contribution to journalArticle

119 Citations (Scopus)

Abstract

Nonresponse to treatment in obsessive-compulsive disorder is common, associated with substantial impairment, and understudied. Little practical advice is available to clinicians on next-step treatment strategies for patients who have not responded well to 2 trials of selective serotonin reuptake inhibitors (SSRIs). Available options include continuation of SSRI treatment, switching to another SSRI or selective serotonin-norepinephrine reuptake inhibitor, augmenting with atypical neuroleptics or cognitive-behavioral therapy, or utilizing novel treatment approaches. The authors synthesize state-of-the-art treatment and give practical advice for clinicians.

Original languageEnglish (US)
Pages (from-to)20-29
Number of pages10
JournalJournal of Clinical Psychiatry
Volume63
Issue numberSUPPL. 6
StatePublished - 2002
Externally publishedYes

Fingerprint

Obsessive-Compulsive Disorder
Serotonin Uptake Inhibitors
Therapeutics
Cognitive Therapy
Antipsychotic Agents

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Hollander, E., Bienstock, C. A., Koran, L. M., Pallanti, S., Marazziti, D., Rasmussen, S. A., ... Zohar, J. (2002). Refractory obsessive-compulsive disorder: State-of-the-art treatment. Journal of Clinical Psychiatry, 63(SUPPL. 6), 20-29.

Refractory obsessive-compulsive disorder : State-of-the-art treatment. / Hollander, Eric; Bienstock, Carol A.; Koran, Lorrin M.; Pallanti, Stefano; Marazziti, Donatella; Rasmussen, Steven A.; Ravizza, Luigi; Benkelfat, Chawkie; Saxena, Sanjaya; Greenberg, Benjamin D.; Sasson, Yehuda; Zohar, Joseph.

In: Journal of Clinical Psychiatry, Vol. 63, No. SUPPL. 6, 2002, p. 20-29.

Research output: Contribution to journalArticle

Hollander, E, Bienstock, CA, Koran, LM, Pallanti, S, Marazziti, D, Rasmussen, SA, Ravizza, L, Benkelfat, C, Saxena, S, Greenberg, BD, Sasson, Y & Zohar, J 2002, 'Refractory obsessive-compulsive disorder: State-of-the-art treatment', Journal of Clinical Psychiatry, vol. 63, no. SUPPL. 6, pp. 20-29.
Hollander E, Bienstock CA, Koran LM, Pallanti S, Marazziti D, Rasmussen SA et al. Refractory obsessive-compulsive disorder: State-of-the-art treatment. Journal of Clinical Psychiatry. 2002;63(SUPPL. 6):20-29.
Hollander, Eric ; Bienstock, Carol A. ; Koran, Lorrin M. ; Pallanti, Stefano ; Marazziti, Donatella ; Rasmussen, Steven A. ; Ravizza, Luigi ; Benkelfat, Chawkie ; Saxena, Sanjaya ; Greenberg, Benjamin D. ; Sasson, Yehuda ; Zohar, Joseph. / Refractory obsessive-compulsive disorder : State-of-the-art treatment. In: Journal of Clinical Psychiatry. 2002 ; Vol. 63, No. SUPPL. 6. pp. 20-29.
@article{3e5b4e6bab6c4d2ea51c9c0e600fa4cd,
title = "Refractory obsessive-compulsive disorder: State-of-the-art treatment",
abstract = "Nonresponse to treatment in obsessive-compulsive disorder is common, associated with substantial impairment, and understudied. Little practical advice is available to clinicians on next-step treatment strategies for patients who have not responded well to 2 trials of selective serotonin reuptake inhibitors (SSRIs). Available options include continuation of SSRI treatment, switching to another SSRI or selective serotonin-norepinephrine reuptake inhibitor, augmenting with atypical neuroleptics or cognitive-behavioral therapy, or utilizing novel treatment approaches. The authors synthesize state-of-the-art treatment and give practical advice for clinicians.",
author = "Eric Hollander and Bienstock, {Carol A.} and Koran, {Lorrin M.} and Stefano Pallanti and Donatella Marazziti and Rasmussen, {Steven A.} and Luigi Ravizza and Chawkie Benkelfat and Sanjaya Saxena and Greenberg, {Benjamin D.} and Yehuda Sasson and Joseph Zohar",
year = "2002",
language = "English (US)",
volume = "63",
pages = "20--29",
journal = "Journal of Clinical Psychiatry",
issn = "0160-6689",
publisher = "Physicians Postgraduate Press Inc.",
number = "SUPPL. 6",

}

TY - JOUR

T1 - Refractory obsessive-compulsive disorder

T2 - State-of-the-art treatment

AU - Hollander, Eric

AU - Bienstock, Carol A.

AU - Koran, Lorrin M.

AU - Pallanti, Stefano

AU - Marazziti, Donatella

AU - Rasmussen, Steven A.

AU - Ravizza, Luigi

AU - Benkelfat, Chawkie

AU - Saxena, Sanjaya

AU - Greenberg, Benjamin D.

AU - Sasson, Yehuda

AU - Zohar, Joseph

PY - 2002

Y1 - 2002

N2 - Nonresponse to treatment in obsessive-compulsive disorder is common, associated with substantial impairment, and understudied. Little practical advice is available to clinicians on next-step treatment strategies for patients who have not responded well to 2 trials of selective serotonin reuptake inhibitors (SSRIs). Available options include continuation of SSRI treatment, switching to another SSRI or selective serotonin-norepinephrine reuptake inhibitor, augmenting with atypical neuroleptics or cognitive-behavioral therapy, or utilizing novel treatment approaches. The authors synthesize state-of-the-art treatment and give practical advice for clinicians.

AB - Nonresponse to treatment in obsessive-compulsive disorder is common, associated with substantial impairment, and understudied. Little practical advice is available to clinicians on next-step treatment strategies for patients who have not responded well to 2 trials of selective serotonin reuptake inhibitors (SSRIs). Available options include continuation of SSRI treatment, switching to another SSRI or selective serotonin-norepinephrine reuptake inhibitor, augmenting with atypical neuroleptics or cognitive-behavioral therapy, or utilizing novel treatment approaches. The authors synthesize state-of-the-art treatment and give practical advice for clinicians.

UR - http://www.scopus.com/inward/record.url?scp=0036231557&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036231557&partnerID=8YFLogxK

M3 - Article

C2 - 12027116

AN - SCOPUS:0036231557

VL - 63

SP - 20

EP - 29

JO - Journal of Clinical Psychiatry

JF - Journal of Clinical Psychiatry

SN - 0160-6689

IS - SUPPL. 6

ER -