Rating of medication influences (ROMI) scale in schizophrenia

Peter Weiden, Bruce Rapkin, Tasha Mott, Annette Zygmunt, Dodi Goldman, Marcela Horvitz-lennon, Allen Frances

Research output: Contribution to journalArticle

259 Scopus citations


Noncompliance with neuroleptic treatment is a major barrier to delivery of effective treatment for schizophrenia outpatients. This article describes the development of a standardized measure for the assessment of attitudinal and behavioral factors influencing patient compliance with neuroleptic treatment. The Rating of Medication Influences (ROMI) scale was developed as part of a longitudinal study of neuroleptic noncompliance in schizophrenia and administered to 115 discharged schizophrenia outpatients. Analyses of the following were conducted to assess the scale's psychometric properties: (1) interrater reliability, (2) internal consistency, (3) principal components, (4) correlation with other subjective measures, and (5) correlation with independent family reports. Most (95%) of the ROMI patient-report items were reliable, whereas rater-judgment items were not reliable. The rater section was dropped. A principal components analysis of the reliable patient-report items yielded three subscales related to compliance (Prevention, Influence of Others, and Medication Affinity) and five subscales related to noncompliance (Denial/Dysphoria, Logistical Problems, Rejection of Label, Family Influence, and Negative Therapeutic Alliance). There were significant correlations between these subscales, and independently obtained family-report ROMI items were significant. The Denial/Dysphoria subscale correlated strongly with two other published measures of dysphoric response to neuroleptics, whereas the other noncompliance sub-scales did not. The ROMI is a reliable and valid instrument that can be used to assess the patient's subjective reasons for medication compliance and noncompliance. The subscale findings suggest that the ROMI provides a more comprehensive data base for patient-reported compliance attitudes than the other available subjective measures. Indications for use of the ROMI and other subjective measures of neuroleptic response are reviewed.

Original languageEnglish (US)
Pages (from-to)297-310
Number of pages14
JournalSchizophrenia Bulletin
Issue number2
StatePublished - Dec 1 1994
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Weiden, P., Rapkin, B., Mott, T., Zygmunt, A., Goldman, D., Horvitz-lennon, M., & Frances, A. (1994). Rating of medication influences (ROMI) scale in schizophrenia. Schizophrenia Bulletin, 20(2), 297-310. https://doi.org/10.1093/schbul/20.2.297