Rare Optic Neuropathy in a Jamaican Couple Linked to Cassava Root Consumption

Sruti S. Akella, Geulah S. Ben-David, Jeffrey S. Schultz, Cheng Zhang

Research output: Contribution to journalArticle

Abstract

We report central visual loss with selective papillomacular bundle damage in a Jamaican couple, husband and wife, with long-term cassava root consumption. The two cases presented independently with gradual central visual loss. Examination revealed bilateral temporal pallor of the optic nerve head and automated static perimetry demonstrated a central or caecocentral scotoma in each patient. Optical coherence tomography findings are described. The only mutual risk factor, reported independently, was long-term cassava consumption. Cessation of cassava intake and vitamin supplementation resulted in partial recovery of visual function. As thiocyanate levels in urine were not measured, the aetiology in these patients is not definitively confirmed, but chronic cassava consumption should be considered in similar cases as a rare cause of potentially reversible optic neuropathy.

Original languageEnglish (US)
JournalNeuro-Ophthalmology
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Manihot
Optic Nerve Diseases
Spouses
Pallor
Scotoma
Visual Field Tests
Optic Disk
Recovery of Function
Optical Coherence Tomography
Vitamins
Urine

Keywords

  • Cassava
  • central scotoma
  • cyanide
  • papillomacular bundle
  • toxic optic neuropathy

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

Cite this

Rare Optic Neuropathy in a Jamaican Couple Linked to Cassava Root Consumption. / Akella, Sruti S.; Ben-David, Geulah S.; Schultz, Jeffrey S.; Zhang, Cheng.

In: Neuro-Ophthalmology, 01.01.2018.

Research output: Contribution to journalArticle

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