Rapid human immunodeficiency virus-1 testing on labor and delivery in 17 US hospitals: the MIRIAD experience

Denise J. Jamieson, Mardge H. Cohen, Robert Maupin, Steven Nesheim, Susan P. Danner, Margaret A. Lampe, Mary Jo O'Sullivan, Mayris P. Webber, Jeffrey Wiener, Rosalind J. Carter, Yvette Rivero, Mary Glenn Fowler, Marc Bulterys

Research output: Contribution to journalReview article

32 Scopus citations

Abstract

The objective of the study was to evaluate the feasibility, acceptability, and accuracy of rapid human immunodeficiency virus (HIV) testing during labor. The Mother-Infant Rapid Intervention at Delivery (MIRIAD) study was a prospective, multicenter study that offered voluntary, rapid HIV testing to women with undocumented HIV status at 17 hospitals in 6 cities. Of 12,481 eligible women, 74% were approached for participation and 85.5% of those approached accepted rapid HIV testing. Among 7753 women tested, MIRIAD identified 52 (0.7%) HIV-infected women. The time between obtaining the blood sample for the rapid test and reporting the results to the health care provider was shorter for hospitals utilizing point-of-care testing than in hospitals utilizing laboratory-based testing (30 minutes vs 68 minutes; P < .0001), and point-of-care testing strategies were 14 times more likely to have a short turnaround as laboratory testing strategies. Routine rapid testing during labor provides a feasible, acceptable, and accurate way to identify HIV-infected women before delivery.

Original languageEnglish (US)
Pages (from-to)S72-S82
JournalAmerican journal of obstetrics and gynecology
Volume197
Issue number3 SUPPL.
DOIs
StatePublished - Sep 1 2007

Keywords

  • rapid human immunodeficiency virus testing

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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