Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction

John J. Bergan, Frank J. Veith, Victor M. Bernhard, James S T Yao, William R. Flinn, Sushil K. Gupta, Larry A. Scher, Russell H. Samson, Jonathan B. Towne

Research output: Contribution to journalArticle

187 Citations (Scopus)

Abstract

A randomized, prospective, controlled study comparing autogenous saphenous vein and polytetrafluoroethylene (PTFE) grafts in infrainguinal arterial reconstructions has been initiated in three different institutions. A total of 446 operative procedures were divided into six groups, depending on the site of distal bypass insertion into the popliteal or an infrapopliteal artery and on whether the patient received a randomized vein or PTFE graft or an obligatory PTFE graft. The randomized saphenous vein graft patency to infrapopliteal arteries was significantly better (P < 0.005) at 2 1 2 years than the patency of randomized or obligatory PTFE grafts to the same level. No significant differences between randomized vein grafts and randomized or obligatory PTFE grafts in the femoropopliteal position could be demonstrated up to 2 1 2 years, either above or below the knee. The need for such a study and the limitations of this preliminary report are discussed. The requirement for longer observation of greater numbers of cases is stressed. A current plan for usage of the PTFE graft in the lower extremity is presented.

Original languageEnglish (US)
Pages (from-to)921-930
Number of pages10
JournalSurgery
Volume92
Issue number6
StatePublished - 1982

Fingerprint

Polytetrafluoroethylene
Random Allocation
Thigh
Veins
Transplants
Saphenous Vein
Arteries
Operative Surgical Procedures
Lower Extremity
Knee
Observation
Prospective Studies

ASJC Scopus subject areas

  • Surgery

Cite this

Bergan, J. J., Veith, F. J., Bernhard, V. M., Yao, J. S. T., Flinn, W. R., Gupta, S. K., ... Towne, J. B. (1982). Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction. Surgery, 92(6), 921-930.

Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction. / Bergan, John J.; Veith, Frank J.; Bernhard, Victor M.; Yao, James S T; Flinn, William R.; Gupta, Sushil K.; Scher, Larry A.; Samson, Russell H.; Towne, Jonathan B.

In: Surgery, Vol. 92, No. 6, 1982, p. 921-930.

Research output: Contribution to journalArticle

Bergan, JJ, Veith, FJ, Bernhard, VM, Yao, JST, Flinn, WR, Gupta, SK, Scher, LA, Samson, RH & Towne, JB 1982, 'Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction', Surgery, vol. 92, no. 6, pp. 921-930.
Bergan JJ, Veith FJ, Bernhard VM, Yao JST, Flinn WR, Gupta SK et al. Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction. Surgery. 1982;92(6):921-930.
Bergan, John J. ; Veith, Frank J. ; Bernhard, Victor M. ; Yao, James S T ; Flinn, William R. ; Gupta, Sushil K. ; Scher, Larry A. ; Samson, Russell H. ; Towne, Jonathan B. / Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction. In: Surgery. 1982 ; Vol. 92, No. 6. pp. 921-930.
@article{445a8c47c07745c6a79a49734b34c0be,
title = "Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction",
abstract = "A randomized, prospective, controlled study comparing autogenous saphenous vein and polytetrafluoroethylene (PTFE) grafts in infrainguinal arterial reconstructions has been initiated in three different institutions. A total of 446 operative procedures were divided into six groups, depending on the site of distal bypass insertion into the popliteal or an infrapopliteal artery and on whether the patient received a randomized vein or PTFE graft or an obligatory PTFE graft. The randomized saphenous vein graft patency to infrapopliteal arteries was significantly better (P < 0.005) at 2 1 2 years than the patency of randomized or obligatory PTFE grafts to the same level. No significant differences between randomized vein grafts and randomized or obligatory PTFE grafts in the femoropopliteal position could be demonstrated up to 2 1 2 years, either above or below the knee. The need for such a study and the limitations of this preliminary report are discussed. The requirement for longer observation of greater numbers of cases is stressed. A current plan for usage of the PTFE graft in the lower extremity is presented.",
author = "Bergan, {John J.} and Veith, {Frank J.} and Bernhard, {Victor M.} and Yao, {James S T} and Flinn, {William R.} and Gupta, {Sushil K.} and Scher, {Larry A.} and Samson, {Russell H.} and Towne, {Jonathan B.}",
year = "1982",
language = "English (US)",
volume = "92",
pages = "921--930",
journal = "Surgery (United States)",
issn = "0039-6060",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Randomization of autogenous vein and polytetrafluoroethylene grafts in femoral-distal reconstruction

AU - Bergan, John J.

AU - Veith, Frank J.

AU - Bernhard, Victor M.

AU - Yao, James S T

AU - Flinn, William R.

AU - Gupta, Sushil K.

AU - Scher, Larry A.

AU - Samson, Russell H.

AU - Towne, Jonathan B.

PY - 1982

Y1 - 1982

N2 - A randomized, prospective, controlled study comparing autogenous saphenous vein and polytetrafluoroethylene (PTFE) grafts in infrainguinal arterial reconstructions has been initiated in three different institutions. A total of 446 operative procedures were divided into six groups, depending on the site of distal bypass insertion into the popliteal or an infrapopliteal artery and on whether the patient received a randomized vein or PTFE graft or an obligatory PTFE graft. The randomized saphenous vein graft patency to infrapopliteal arteries was significantly better (P < 0.005) at 2 1 2 years than the patency of randomized or obligatory PTFE grafts to the same level. No significant differences between randomized vein grafts and randomized or obligatory PTFE grafts in the femoropopliteal position could be demonstrated up to 2 1 2 years, either above or below the knee. The need for such a study and the limitations of this preliminary report are discussed. The requirement for longer observation of greater numbers of cases is stressed. A current plan for usage of the PTFE graft in the lower extremity is presented.

AB - A randomized, prospective, controlled study comparing autogenous saphenous vein and polytetrafluoroethylene (PTFE) grafts in infrainguinal arterial reconstructions has been initiated in three different institutions. A total of 446 operative procedures were divided into six groups, depending on the site of distal bypass insertion into the popliteal or an infrapopliteal artery and on whether the patient received a randomized vein or PTFE graft or an obligatory PTFE graft. The randomized saphenous vein graft patency to infrapopliteal arteries was significantly better (P < 0.005) at 2 1 2 years than the patency of randomized or obligatory PTFE grafts to the same level. No significant differences between randomized vein grafts and randomized or obligatory PTFE grafts in the femoropopliteal position could be demonstrated up to 2 1 2 years, either above or below the knee. The need for such a study and the limitations of this preliminary report are discussed. The requirement for longer observation of greater numbers of cases is stressed. A current plan for usage of the PTFE graft in the lower extremity is presented.

UR - http://www.scopus.com/inward/record.url?scp=0020263138&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020263138&partnerID=8YFLogxK

M3 - Article

C2 - 6755789

AN - SCOPUS:0020263138

VL - 92

SP - 921

EP - 930

JO - Surgery (United States)

JF - Surgery (United States)

SN - 0039-6060

IS - 6

ER -