Pyrimethamine concentrations in serum and cerebrospinal fluid during treatment of acute toxoplasma encephalitis in patients with aids

Louis M. Weiss, Carol Harris, Marc Berger, Herbert B. Tanowitz, Murray Wittner, Murray Wittner

Research output: Contribution to journalArticle

52 Scopus citations


Pyrimethamine (PYR) is a substituted phenylpyrimidine compound that has been used as therapy for malaria and is presently the drug of choice for acute toxoplasmosis when combined with trisulfapyrimidines or sulfadiazine. Because of its restricted use, there have been limited studies.

Original languageEnglish (US)
Pages (from-to)580-583
Number of pages4
JournalJournal of Infectious Diseases
Issue number3
StatePublished - Mar 1988


ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

Cite this