Pulmonary vein calcification by EBCT in patients with drug refractory nonvalular atrial fibrillation

James Adams, Andrea Natale, Claude S. Elayi, Luigi Di Biase, David O. Martin, Salwa Beheiry, Steven Hao, Richard Hongo, Chi Keong Ching

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Pulmonary veins in patients with atrial fibrillation (AF) have been shown to be highly arrhythmogenic. Calcification in these veins may play an adjunctive role in the pathogenesis of AF. Methods and Results: A case control study was performed in patients with drug refractory nonvalvular AF whose preablation computed tomography chest scans demonstrated pulmonary vein (PV) calcification. Eight out of 48 patients with PV calcification were compared to 50 patients without AF who underwent electron beam computed tomography coronary artery calcium scores. These patients were matched for age, gender, coronary artery calcium scores, and the presence of PV calcification. The mean age of the combined group was 57±9 years and 60% were men. The mean total PV calcium score was significantly higher at 199±112 in patients with AF compared to 106±52 in controls (p=0.018). Men had significantly higher total PV calcium score than women in both groups. Conclusion: Total PV calcium score was significantly higher in patients with atrial fibrillation. Increased PV calcification may play an adjunctive role in the pathogenesis in initiating and maintaining AF.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalJournal of Interventional Cardiac Electrophysiology
Volume22
Issue number3
DOIs
StatePublished - Sep 2008
Externally publishedYes

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Pulmonary Veins
Atrial Fibrillation
Pharmaceutical Preparations
Calcium
Coronary Vessels
X Ray Computed Tomography
Case-Control Studies
Veins
Thorax
Age Groups
Tomography

Keywords

  • Ablation
  • Atrial fibrillation
  • Calcification
  • Ct scan

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Pulmonary vein calcification by EBCT in patients with drug refractory nonvalular atrial fibrillation. / Adams, James; Natale, Andrea; Elayi, Claude S.; Di Biase, Luigi; Martin, David O.; Beheiry, Salwa; Hao, Steven; Hongo, Richard; Ching, Chi Keong.

In: Journal of Interventional Cardiac Electrophysiology, Vol. 22, No. 3, 09.2008, p. 173-175.

Research output: Contribution to journalArticle

Adams, James ; Natale, Andrea ; Elayi, Claude S. ; Di Biase, Luigi ; Martin, David O. ; Beheiry, Salwa ; Hao, Steven ; Hongo, Richard ; Ching, Chi Keong. / Pulmonary vein calcification by EBCT in patients with drug refractory nonvalular atrial fibrillation. In: Journal of Interventional Cardiac Electrophysiology. 2008 ; Vol. 22, No. 3. pp. 173-175.
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AU - Martin, David O.

AU - Beheiry, Salwa

AU - Hao, Steven

AU - Hongo, Richard

AU - Ching, Chi Keong

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