TY - JOUR
T1 - Prevalence of lower genital tract infections among human immunodeficiency virus (HIV)-seropositive and high-risk HIV-seronegative women
AU - Cu-Uvin, Susan
AU - Hogan, Joseph W.
AU - Warren, Dora
AU - Klein, Robert S.
AU - Peipert, Jeffrey
AU - Schuman, Paula
AU - Holmberg, Scott
AU - Anderson, Jean
AU - Schoenbaum, Ellie
AU - Vlahov, David
AU - Mayer, Kenneth H.
N1 - Funding Information:
Financial support: Centers for Disease Control and Prevention (cooperative agreements no. U64CU106795, U64CU20678, U64CU306802, and U64CU506831).
PY - 1999
Y1 - 1999
N2 - This study was undertaken to assess whether the prevalence of lower genital tract infections among human immunodeficiency virus (HIV)- seropositive women was higher than among high-risk HIV-seronegative women at their baseline visit for the HIV Epidemiology Research Study. Results were available for 851 HIV-seropositive and 434 HIV-seronegative women. Human papilloma virus (HPV) infection was more prevalent among HIV-seropositive women (64% vs. 28%). Bacterial vaginosis was common (35% vs. 33%), followed by trichomoniasis (12% vs. 10%), syphilis (8% vs. 6%), Chlamydia trachomatis infection (4% vs. 5%), candidal vaginitis (3% vs. 2%), and Neisseria gonorrhoeae infection (0.8% vs. 0.3%). Alcohol use (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.3-2.4) and smoking (OR, 1.8; 95% CI, 1.3-2.5) were associated with bacterial vaginosis. Bacterial vaginosis (OR, 2.3; 95% CI, 1.5-3.4), trichomoniasis (OR, 2.3; 95% CI, 1.1-4.7), and syphilis (OR, 3.1; 95% CI, 1.3-7.4) were found to be more prevalent among black women. Our study showed no statistically significant difference in the prevalence of lower genital tract infections except for HPV between HIV-infected and demographically and behaviorally similar HIV-uninfected high-risk women.
AB - This study was undertaken to assess whether the prevalence of lower genital tract infections among human immunodeficiency virus (HIV)- seropositive women was higher than among high-risk HIV-seronegative women at their baseline visit for the HIV Epidemiology Research Study. Results were available for 851 HIV-seropositive and 434 HIV-seronegative women. Human papilloma virus (HPV) infection was more prevalent among HIV-seropositive women (64% vs. 28%). Bacterial vaginosis was common (35% vs. 33%), followed by trichomoniasis (12% vs. 10%), syphilis (8% vs. 6%), Chlamydia trachomatis infection (4% vs. 5%), candidal vaginitis (3% vs. 2%), and Neisseria gonorrhoeae infection (0.8% vs. 0.3%). Alcohol use (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.3-2.4) and smoking (OR, 1.8; 95% CI, 1.3-2.5) were associated with bacterial vaginosis. Bacterial vaginosis (OR, 2.3; 95% CI, 1.5-3.4), trichomoniasis (OR, 2.3; 95% CI, 1.1-4.7), and syphilis (OR, 3.1; 95% CI, 1.3-7.4) were found to be more prevalent among black women. Our study showed no statistically significant difference in the prevalence of lower genital tract infections except for HPV between HIV-infected and demographically and behaviorally similar HIV-uninfected high-risk women.
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U2 - 10.1086/313434
DO - 10.1086/313434
M3 - Article
C2 - 10524955
AN - SCOPUS:0033503174
SN - 1058-4838
VL - 29
SP - 1145
EP - 1150
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 5
ER -