Abstract
Aim: Financial toxicity (FT) describes patients' burden from out-of-pocket medical treatment costs. We studied associations between patient-reported pretreatment FT, socioeconomic status and clinical outcomes for locally advanced non-small-cell lung cancer (LA-NSCLC) patients. Methods: Patients received chemoradiotherapy for locally advanced non-small-cell lung cancer and completed the European Organization for the Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) quality of life assessment before treatment. One question asks whether patients experience financial difficulties'. We tested FT and socioeconomic status (SES) as predictors of progression-free survival (PFS) and overall survival (OS). Results: A total of 43 patients were included. Median follow-up for surviving patients was 15 months. A total of 19 patients (44%) experienced disease progression and 17 patients (40%) died. Increasing FT was associated with shorter PFS (p = 0.011). FT did not predict overall survival (p = 0.67). Conclusion: Higher pretreatment FT is associated with shorter PFS.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1697-1705 |
| Number of pages | 9 |
| Journal | Future Oncology |
| Volume | 15 |
| Issue number | 15 |
| DOIs | |
| State | Published - May 2019 |
Keywords
- chemoradiotherapy
- chemotherapy
- financial toxicity
- lung cancer
- non-small-cell lung cancer
- quality of life
- radiation therapy
ASJC Scopus subject areas
- Oncology
- Cancer Research
