Prenatal diagnosis of a de novo unbalanced translocation (4p + ) following in vitro fertilization

Linda A. Cannizzaro, Barbara K. Hecht, Helen A. Bixenman, Stephen Pazdziorko, Robert Tamis, Frederick Hecht

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We report herein a de novo unbalanced chromosome translocation in a fetus resulting from in vitro fertilization technology. Prenatal diagnostic analysis of an amniotic fluid revealed a 46,XX,4p+ karyotype. The origin of the extra material on the short arm of chromosome 4 could not be identified by a variety of banding techniques. However, examination of fetal parts did reveal some dysmorphic features.

Original languageEnglish (US)
Pages (from-to)297-301
Number of pages5
JournalPrenatal Diagnosis
Volume8
Issue number4
DOIs
Publication statusPublished - May 1988

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Keywords

  • 4p+ Translocation
  • in vitro fertilization

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Genetics(clinical)

Cite this

Cannizzaro, L. A., Hecht, B. K., Bixenman, H. A., Pazdziorko, S., Tamis, R., & Hecht, F. (1988). Prenatal diagnosis of a de novo unbalanced translocation (4p + ) following in vitro fertilization. Prenatal Diagnosis, 8(4), 297-301. https://doi.org/10.1002/pd.1970080409