Preliminary results with dye enhanced selective laser sclerosis of venous varicosities

Steven K. Libutti, Mehmet C. Oz, Roy S. Chuck, Joseph S. Auteri, Hanina Hibshoosh, Roman Nowygrod, Michael R. Treat

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Laser sclerosis (photosclerosis) of veins after injection of wavelength-specific dyes to enhance and localize energy absorption could provide a useful adjunct to current treatment options. To enhance the absorption of 808nm diode laser energy, ear veins of 18 rabbits were infused with 2-3cc of indocyanine green (maximum absorption 805nm) and exposed for 2 to 20 seconds. Animals were sacrificed between 0 and 28 days after operation. Discrete time intervals of laser exposure exist during which various sized vessels can be photosclerosed without significant thermal injury to the overlying tissue. The use of low power, diode lasers, in conjunction with wavelength-specific dyes, may provide a simple, effective, and cosmetically appealling alternative to current treatment options for superficial varicosities of the extremities.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsStephen N. Joffe, Kazuhiko Atsumi
PublisherPubl by Int Soc for Optical Engineering
Pages172-176
Number of pages5
ISBN (Print)0819402419
Publication statusPublished - Dec 1 1990
EventProceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II - Los Angeles, CA, USA
Duration: Jan 14 1990Jan 19 1990

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1200
ISSN (Print)0277-786X

Other

OtherProceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II
CityLos Angeles, CA, USA
Period1/14/901/19/90

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Libutti, S. K., Oz, M. C., Chuck, R. S., Auteri, J. S., Hibshoosh, H., Nowygrod, R., & Treat, M. R. (1990). Preliminary results with dye enhanced selective laser sclerosis of venous varicosities. In S. N. Joffe, & K. Atsumi (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (pp. 172-176). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1200). Publ by Int Soc for Optical Engineering.