Preliminary results with dye enhanced selective laser sclerosis of venous varicosities

Steven K. Libutti, Mehmet C. Oz, Roy S. Chuck, Joseph S. Auteri, Hanina Hibshoosh, Roman Nowygrod, Michael R. Treat

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Laser sclerosis (photosclerosis) of veins after injection of wavelength-specific dyes to enhance and localize energy absorption could provide a useful adjunct to current treatment options. To enhance the absorption of 808nm diode laser energy, ear veins of 18 rabbits were infused with 2-3cc of indocyanine green (maximum absorption 805nm) and exposed for 2 to 20 seconds. Animals were sacrificed between 0 and 28 days after operation. Discrete time intervals of laser exposure exist during which various sized vessels can be photosclerosed without significant thermal injury to the overlying tissue. The use of low power, diode lasers, in conjunction with wavelength-specific dyes, may provide a simple, effective, and cosmetically appealling alternative to current treatment options for superficial varicosities of the extremities.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsStephen N. Joffe, Kazuhiko Atsumi
PublisherPubl by Int Soc for Optical Engineering
Pages172-176
Number of pages5
Volume1200
ISBN (Print)0819402419
StatePublished - 1990
Externally publishedYes
EventProceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II - Los Angeles, CA, USA
Duration: Jan 14 1990Jan 19 1990

Other

OtherProceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II
CityLos Angeles, CA, USA
Period1/14/901/19/90

Fingerprint

veins
Semiconductor lasers
Dyes
dyes
semiconductor lasers
Wavelength
Lasers
rabbits
energy absorption
Energy absorption
ear
wavelengths
lasers
vessels
animals
Animals
Tissue
injection
intervals
energy

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Libutti, S. K., Oz, M. C., Chuck, R. S., Auteri, J. S., Hibshoosh, H., Nowygrod, R., & Treat, M. R. (1990). Preliminary results with dye enhanced selective laser sclerosis of venous varicosities. In S. N. Joffe, & K. Atsumi (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 1200, pp. 172-176). Publ by Int Soc for Optical Engineering.

Preliminary results with dye enhanced selective laser sclerosis of venous varicosities. / Libutti, Steven K.; Oz, Mehmet C.; Chuck, Roy S.; Auteri, Joseph S.; Hibshoosh, Hanina; Nowygrod, Roman; Treat, Michael R.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Stephen N. Joffe; Kazuhiko Atsumi. Vol. 1200 Publ by Int Soc for Optical Engineering, 1990. p. 172-176.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Libutti, SK, Oz, MC, Chuck, RS, Auteri, JS, Hibshoosh, H, Nowygrod, R & Treat, MR 1990, Preliminary results with dye enhanced selective laser sclerosis of venous varicosities. in SN Joffe & K Atsumi (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 1200, Publ by Int Soc for Optical Engineering, pp. 172-176, Proceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II, Los Angeles, CA, USA, 1/14/90.
Libutti SK, Oz MC, Chuck RS, Auteri JS, Hibshoosh H, Nowygrod R et al. Preliminary results with dye enhanced selective laser sclerosis of venous varicosities. In Joffe SN, Atsumi K, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1200. Publ by Int Soc for Optical Engineering. 1990. p. 172-176
Libutti, Steven K. ; Oz, Mehmet C. ; Chuck, Roy S. ; Auteri, Joseph S. ; Hibshoosh, Hanina ; Nowygrod, Roman ; Treat, Michael R. / Preliminary results with dye enhanced selective laser sclerosis of venous varicosities. Proceedings of SPIE - The International Society for Optical Engineering. editor / Stephen N. Joffe ; Kazuhiko Atsumi. Vol. 1200 Publ by Int Soc for Optical Engineering, 1990. pp. 172-176
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abstract = "Laser sclerosis (photosclerosis) of veins after injection of wavelength-specific dyes to enhance and localize energy absorption could provide a useful adjunct to current treatment options. To enhance the absorption of 808nm diode laser energy, ear veins of 18 rabbits were infused with 2-3cc of indocyanine green (maximum absorption 805nm) and exposed for 2 to 20 seconds. Animals were sacrificed between 0 and 28 days after operation. Discrete time intervals of laser exposure exist during which various sized vessels can be photosclerosed without significant thermal injury to the overlying tissue. The use of low power, diode lasers, in conjunction with wavelength-specific dyes, may provide a simple, effective, and cosmetically appealling alternative to current treatment options for superficial varicosities of the extremities.",
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