Predictors of HIV infection among newly sentenced male prisoners

Frederick L. Altice, Farzad Mostashari, Peter A. Selwyn, Patricia J. Checko, Ratan Singh, Sandy Tanguay, Edward A. Blanchette

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

The prevalence of individuals with or at risk for HIV infection in prisons and jails is severalfold higher than age-adjusted rates in surrounding communities. This HIV serosurvey of 975 newly sentenced male prisoners employed a new methodology that anonymously linked individual information to HIV serologic data. The HIV prevalence was 6.1%; multivariate regression analysis indicated injection drug use (OR = 18.9), black race (OR = 5.5), Hispanic ethnicity (OR = 3.4), psychiatric illness (OR = 3.1) and a history of having had a sexually transmitted disease (OR = 2.2) were independent predictors of HIV infection. Laboratory markers such as hypoalbuminemia, an elevated aspartate aminotransferase (AST) level, leukopenia, anemia, and thrombocytopenia suggest increased risk for HIV among prisoners, particularly in settings where HIV testing resources are scarce. This study, unlike those reported in other geographic regions, indicated that the majority (71%) of HIV-seropositive persons self-reported their HIV status. This finding may suggest that HIV-infected individuals will self- report their status if HIV care is comprehensive and consistent. The large number of HIV-infected individuals within prisons makes prisons important sites for the introduction of comprehensive HIV-related care. This is particularly relevant in that development of new guidelines issued for the management of HIV infection in which potent combination antiretroviral therapy has been demonstrated to decrease morbidity and mortality. The high prevalence of HIV-seronegative inmates with self-reported high-risk behaviors also suggests the importance of prisons as sites for the introduction of appropriate risk-reduction interventions.

Original languageEnglish (US)
Pages (from-to)444-453
Number of pages10
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Volume18
Issue number5
StatePublished - Aug 15 1998
Externally publishedYes

Fingerprint

Prisoners
HIV Infections
HIV
Prisons
Hypoalbuminemia
Leukopenia
Risk Reduction Behavior
Sexually Transmitted Diseases
Aspartate Aminotransferases
Risk-Taking
Hispanic Americans
Thrombocytopenia
Self Report
Psychiatry
Anemia
Multivariate Analysis
Biomarkers
Regression Analysis

Keywords

  • Black race
  • HIV prevalence
  • Hypoalbuminemia
  • Injecting drug use
  • Mental illness
  • Prevention
  • Prisoners
  • Sexually transmitted diseases

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Virology

Cite this

Altice, F. L., Mostashari, F., Selwyn, P. A., Checko, P. J., Singh, R., Tanguay, S., & Blanchette, E. A. (1998). Predictors of HIV infection among newly sentenced male prisoners. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 18(5), 444-453.

Predictors of HIV infection among newly sentenced male prisoners. / Altice, Frederick L.; Mostashari, Farzad; Selwyn, Peter A.; Checko, Patricia J.; Singh, Ratan; Tanguay, Sandy; Blanchette, Edward A.

In: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, Vol. 18, No. 5, 15.08.1998, p. 444-453.

Research output: Contribution to journalArticle

Altice, FL, Mostashari, F, Selwyn, PA, Checko, PJ, Singh, R, Tanguay, S & Blanchette, EA 1998, 'Predictors of HIV infection among newly sentenced male prisoners', Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, vol. 18, no. 5, pp. 444-453.
Altice, Frederick L. ; Mostashari, Farzad ; Selwyn, Peter A. ; Checko, Patricia J. ; Singh, Ratan ; Tanguay, Sandy ; Blanchette, Edward A. / Predictors of HIV infection among newly sentenced male prisoners. In: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 1998 ; Vol. 18, No. 5. pp. 444-453.
@article{0823ead874fe46f8a7248fe8969ceb6b,
title = "Predictors of HIV infection among newly sentenced male prisoners",
abstract = "The prevalence of individuals with or at risk for HIV infection in prisons and jails is severalfold higher than age-adjusted rates in surrounding communities. This HIV serosurvey of 975 newly sentenced male prisoners employed a new methodology that anonymously linked individual information to HIV serologic data. The HIV prevalence was 6.1{\%}; multivariate regression analysis indicated injection drug use (OR = 18.9), black race (OR = 5.5), Hispanic ethnicity (OR = 3.4), psychiatric illness (OR = 3.1) and a history of having had a sexually transmitted disease (OR = 2.2) were independent predictors of HIV infection. Laboratory markers such as hypoalbuminemia, an elevated aspartate aminotransferase (AST) level, leukopenia, anemia, and thrombocytopenia suggest increased risk for HIV among prisoners, particularly in settings where HIV testing resources are scarce. This study, unlike those reported in other geographic regions, indicated that the majority (71{\%}) of HIV-seropositive persons self-reported their HIV status. This finding may suggest that HIV-infected individuals will self- report their status if HIV care is comprehensive and consistent. The large number of HIV-infected individuals within prisons makes prisons important sites for the introduction of comprehensive HIV-related care. This is particularly relevant in that development of new guidelines issued for the management of HIV infection in which potent combination antiretroviral therapy has been demonstrated to decrease morbidity and mortality. The high prevalence of HIV-seronegative inmates with self-reported high-risk behaviors also suggests the importance of prisons as sites for the introduction of appropriate risk-reduction interventions.",
keywords = "Black race, HIV prevalence, Hypoalbuminemia, Injecting drug use, Mental illness, Prevention, Prisoners, Sexually transmitted diseases",
author = "Altice, {Frederick L.} and Farzad Mostashari and Selwyn, {Peter A.} and Checko, {Patricia J.} and Ratan Singh and Sandy Tanguay and Blanchette, {Edward A.}",
year = "1998",
month = "8",
day = "15",
language = "English (US)",
volume = "18",
pages = "444--453",
journal = "Journal of Acquired Immune Deficiency Syndromes",
issn = "1525-4135",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Predictors of HIV infection among newly sentenced male prisoners

AU - Altice, Frederick L.

AU - Mostashari, Farzad

AU - Selwyn, Peter A.

AU - Checko, Patricia J.

AU - Singh, Ratan

AU - Tanguay, Sandy

AU - Blanchette, Edward A.

PY - 1998/8/15

Y1 - 1998/8/15

N2 - The prevalence of individuals with or at risk for HIV infection in prisons and jails is severalfold higher than age-adjusted rates in surrounding communities. This HIV serosurvey of 975 newly sentenced male prisoners employed a new methodology that anonymously linked individual information to HIV serologic data. The HIV prevalence was 6.1%; multivariate regression analysis indicated injection drug use (OR = 18.9), black race (OR = 5.5), Hispanic ethnicity (OR = 3.4), psychiatric illness (OR = 3.1) and a history of having had a sexually transmitted disease (OR = 2.2) were independent predictors of HIV infection. Laboratory markers such as hypoalbuminemia, an elevated aspartate aminotransferase (AST) level, leukopenia, anemia, and thrombocytopenia suggest increased risk for HIV among prisoners, particularly in settings where HIV testing resources are scarce. This study, unlike those reported in other geographic regions, indicated that the majority (71%) of HIV-seropositive persons self-reported their HIV status. This finding may suggest that HIV-infected individuals will self- report their status if HIV care is comprehensive and consistent. The large number of HIV-infected individuals within prisons makes prisons important sites for the introduction of comprehensive HIV-related care. This is particularly relevant in that development of new guidelines issued for the management of HIV infection in which potent combination antiretroviral therapy has been demonstrated to decrease morbidity and mortality. The high prevalence of HIV-seronegative inmates with self-reported high-risk behaviors also suggests the importance of prisons as sites for the introduction of appropriate risk-reduction interventions.

AB - The prevalence of individuals with or at risk for HIV infection in prisons and jails is severalfold higher than age-adjusted rates in surrounding communities. This HIV serosurvey of 975 newly sentenced male prisoners employed a new methodology that anonymously linked individual information to HIV serologic data. The HIV prevalence was 6.1%; multivariate regression analysis indicated injection drug use (OR = 18.9), black race (OR = 5.5), Hispanic ethnicity (OR = 3.4), psychiatric illness (OR = 3.1) and a history of having had a sexually transmitted disease (OR = 2.2) were independent predictors of HIV infection. Laboratory markers such as hypoalbuminemia, an elevated aspartate aminotransferase (AST) level, leukopenia, anemia, and thrombocytopenia suggest increased risk for HIV among prisoners, particularly in settings where HIV testing resources are scarce. This study, unlike those reported in other geographic regions, indicated that the majority (71%) of HIV-seropositive persons self-reported their HIV status. This finding may suggest that HIV-infected individuals will self- report their status if HIV care is comprehensive and consistent. The large number of HIV-infected individuals within prisons makes prisons important sites for the introduction of comprehensive HIV-related care. This is particularly relevant in that development of new guidelines issued for the management of HIV infection in which potent combination antiretroviral therapy has been demonstrated to decrease morbidity and mortality. The high prevalence of HIV-seronegative inmates with self-reported high-risk behaviors also suggests the importance of prisons as sites for the introduction of appropriate risk-reduction interventions.

KW - Black race

KW - HIV prevalence

KW - Hypoalbuminemia

KW - Injecting drug use

KW - Mental illness

KW - Prevention

KW - Prisoners

KW - Sexually transmitted diseases

UR - http://www.scopus.com/inward/record.url?scp=0032529606&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032529606&partnerID=8YFLogxK

M3 - Article

C2 - 9715840

AN - SCOPUS:0032529606

VL - 18

SP - 444

EP - 453

JO - Journal of Acquired Immune Deficiency Syndromes

JF - Journal of Acquired Immune Deficiency Syndromes

SN - 1525-4135

IS - 5

ER -