Potential future therapies for the management of cough: ACCP evidence-based clinical practice guidelines

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: When the etiology of a patient's chronic cough is established, specific antitussive therapy that is aimed at a particular cause of cough is highly effective. Nevertheless, in certain situations, therapy with cough suppressants, which previously were classified as nonspecific antitussive therapy, and which aim at suppressing the cough reflex regardless of the cause of cough, will be necessary. Methodology: The data for this review were obtained with the aid of a National Library of Medicine (PubMed) search, which was performed in June 2004, of literature published in the English language from 1966 to 2004, using the search terms "cough," "antitussive," "pharmacotherapy," "future therapies," and "potential therapies." Results/conclusions: Currently available cough-suppressant therapy is severely limited by a dearth of effective agents and/or their unacceptable side effects. Several classes of pharmacologic agents are currently under investigation in an attempt to develop clinically useful cough suppressants.

Original languageEnglish (US)
JournalChest
Volume129
Issue number1 SUPPL.
DOIs
StatePublished - Jan 2006

Fingerprint

Antitussive Agents
Evidence-Based Practice
Practice Guidelines
Cough
Therapeutics
National Library of Medicine (U.S.)
PubMed
Reflex
Language
Drug Therapy

Keywords

  • 5-hydroxytryptamine
  • Antitussive
  • Cannabinoids
  • Capsaicin
  • Cough
  • Future therapies
  • Opioid
  • Potassium channel openers
  • Tachykinins
  • Vanilloid

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Potential future therapies for the management of cough : ACCP evidence-based clinical practice guidelines. / Dicpinigaitis, Peter Vytautas.

In: Chest, Vol. 129, No. 1 SUPPL., 01.2006.

Research output: Contribution to journalArticle

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