Post-9/11 cancer incidence in World Trade Center-exposed New York City firefighters as compared to a pooled cohort of firefighters from San Francisco, Chicago and Philadelphia (9/11/2001-2009)

William Moir, Rachel Zeig-Owens, Robert D. Daniels, Charles B. Hall, Mayris P. Webber, Nadia Jaber, James H. Yiin, Theresa Schwartz, Xiaoxue Liu, Madeline Vossbrinck, Kerry Kelly, David J. Prezant

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: We previously reported a modest excess of cancer in World Trade Center (WTC)-exposed firefighters versus the general population. This study aimed to separate the potential carcinogenic effects of firefighting and WTC exposure by comparing to a cohort of non-WTC-exposed firefighters. Methods: Relative rates (RRs) for all cancers combined and individual cancer subtypes from 9/11/2001 to 12/31/2009 were modeled using Poisson regression comparing 11,457 WTC-exposed firefighters to 8,220 urban non-WTC-exposed firefighters. Results: Compared with non-WTC-exposed firefighters, there was no difference in the RR of all cancers combined for WTC-exposed firefighters (RR = 0.96, 95%CI: 0.83–1.12). Thyroid cancer was significantly elevated (RR = 3.82, 95%CI: 1.07–20.81) from 2001 to 2009; this was attenuated (RR = 3.43, 95%CI: 0.94–18.94) and non-significant when controlling for possible surveillance bias. Prostate cancer was elevated during the latter half (2005–2009; RR = 1.38, 95%CI: 1.01–1.88). Conclusions: Further follow-up is needed to assess the relationship between WTC exposure and cancers with longer latency periods. Am. J. Ind. Med. 59:722–730, 2016.

Original languageEnglish (US)
Pages (from-to)722-730
Number of pages9
JournalAmerican Journal of Industrial Medicine
Volume59
Issue number9
DOIs
StatePublished - Sep 1 2016

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Firefighters
San Francisco
Incidence
Neoplasms
Thyroid Neoplasms
Prostatic Neoplasms
Population

Keywords

  • cancer
  • environmental disaster
  • epidemiology
  • firefighters
  • World Trade Center (WTC)

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Post-9/11 cancer incidence in World Trade Center-exposed New York City firefighters as compared to a pooled cohort of firefighters from San Francisco, Chicago and Philadelphia (9/11/2001-2009). / Moir, William; Zeig-Owens, Rachel; Daniels, Robert D.; Hall, Charles B.; Webber, Mayris P.; Jaber, Nadia; Yiin, James H.; Schwartz, Theresa; Liu, Xiaoxue; Vossbrinck, Madeline; Kelly, Kerry; Prezant, David J.

In: American Journal of Industrial Medicine, Vol. 59, No. 9, 01.09.2016, p. 722-730.

Research output: Contribution to journalArticle

Moir, William ; Zeig-Owens, Rachel ; Daniels, Robert D. ; Hall, Charles B. ; Webber, Mayris P. ; Jaber, Nadia ; Yiin, James H. ; Schwartz, Theresa ; Liu, Xiaoxue ; Vossbrinck, Madeline ; Kelly, Kerry ; Prezant, David J. / Post-9/11 cancer incidence in World Trade Center-exposed New York City firefighters as compared to a pooled cohort of firefighters from San Francisco, Chicago and Philadelphia (9/11/2001-2009). In: American Journal of Industrial Medicine. 2016 ; Vol. 59, No. 9. pp. 722-730.
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