Plasmodium falciparum takes up iron from transferrin

Simeon Pollack, J. Fleming

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Plasmodium falciparum, cultured in vitro, is inhibited by desferrioxamine, a specific iron chelating agent, despite the abundant haem iron which surrounds the parasite. In this report we show that the intraerythrocytic parasite obtains iron from transferrin. The parasite may therefore be freed of a requirement to catabolize haem to obtain iron thus minimizing haem toxicity.

Original languageEnglish (US)
Pages (from-to)289-293
Number of pages5
JournalBritish Journal of Haematology
Volume58
Issue number2
StatePublished - 1984

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Plasmodium falciparum
Transferrin
Heme
Parasites
Iron
Iron Chelating Agents
Deferoxamine

ASJC Scopus subject areas

  • Hematology

Cite this

Plasmodium falciparum takes up iron from transferrin. / Pollack, Simeon; Fleming, J.

In: British Journal of Haematology, Vol. 58, No. 2, 1984, p. 289-293.

Research output: Contribution to journalArticle

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