Plasmodium falciparum takes up iron from transferrin

Simeon Pollack, John Fleming

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Plasmodium falciparum, cultured in vitro, is inhibited by desferrioxamine, a specific iron chelating agent, despite the abundant haem iron which surrounds the parasite. In this report we show that the intraerythrocytic parasite obtains iron from transferrin. The parasite may therefore be freed of a requirement to catabolize haem to obtain iron thus minimizing haem toxicity.

Original languageEnglish (US)
Pages (from-to)289-293
Number of pages5
JournalBritish Journal of Haematology
Volume58
Issue number2
DOIs
StatePublished - Oct 1984

ASJC Scopus subject areas

  • Hematology

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