TY - JOUR
T1 - Plasmodium falciparum takes up iron from transferrin
AU - Pollack, Simeon
AU - Fleming, John
PY - 1984/10
Y1 - 1984/10
N2 - Plasmodium falciparum, cultured in vitro, is inhibited by desferrioxamine, a specific iron chelating agent, despite the abundant haem iron which surrounds the parasite. In this report we show that the intraerythrocytic parasite obtains iron from transferrin. The parasite may therefore be freed of a requirement to catabolize haem to obtain iron thus minimizing haem toxicity.
AB - Plasmodium falciparum, cultured in vitro, is inhibited by desferrioxamine, a specific iron chelating agent, despite the abundant haem iron which surrounds the parasite. In this report we show that the intraerythrocytic parasite obtains iron from transferrin. The parasite may therefore be freed of a requirement to catabolize haem to obtain iron thus minimizing haem toxicity.
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U2 - 10.1111/j.1365-2141.1984.tb06087.x
DO - 10.1111/j.1365-2141.1984.tb06087.x
M3 - Article
C2 - 6383456
AN - SCOPUS:0021163466
SN - 0007-1048
VL - 58
SP - 289
EP - 293
JO - British Journal of Haematology
JF - British Journal of Haematology
IS - 2
ER -