TY - JOUR
T1 - Picture-Based Memory Impairment Screen
T2 - Effective Cognitive Screen in Ethnically Diverse Populations
AU - Malik, Rubina
AU - Weiss, Erica F.
AU - Gottesman, Reena
AU - Zwerling, Jessica
AU - Verghese, Joe
N1 - Funding Information:
Conflict of Interest: None. JV received funding support from National Institute on Aging (NIA) Grants R01 AG039330, RO1AGO44007, PO1 AG03949, RO1AGO44829, and R01AG036921 and National Institute of Neurological Disorders and Stroke (NINDS) Grant 1UG3NS105565–01. JZ received funding support from NIA Grant PO1 AG03949, NINDS Grant 1UG3NS105565–01, the Department of Health CEAD, and a Health Resources and Services Administration Geriatric Work Enhancement Program (GWEP) grant. RM received funding support from NINDS Grant 1UG3NS105565–01, CEAD, and a HRSA GWEP grant. EW received funding support from NIA Grants R01AG057909 and R01AG044829, NINDS Grants R3NS043209 and 1UG3NS105565–01, and CEAD.
Funding Information:
We thank faculty and administrative staff of the Center for the Aging Brain for providing care and data submission. We thank the Department of Health and the Center of Excellence for Alzheimer's Disease (CEAD) for providing support. Conflict of Interest: None. JV received funding support from National Institute on Aging (NIA) Grants R01 AG039330, RO1AGO44007, PO1 AG03949, RO1AGO44829, and R01AG036921 and National Institute of Neurological Disorders and Stroke (NINDS) Grant 1UG3NS105565–01. JZ received funding support from NIA Grant PO1 AG03949, NINDS Grant 1UG3NS105565–01, the Department of Health CEAD, and a Health Resources and Services Administration Geriatric Work Enhancement Program (GWEP) grant. RM received funding support from NINDS Grant 1UG3NS105565–01, CEAD, and a HRSA GWEP grant. EW received funding support from NIA Grants R01AG057909 and R01AG044829, NINDS Grants R3NS043209 and 1UG3NS105565–01, and CEAD. Author Contributions: JV, JZ, EW: study design, data analysis and interpretation, preparation of manuscript. RM, RG, EW: data collection, analysis, and interpretation; preparation of manuscript. Sponsor's Role: Not applicable.
Publisher Copyright:
© 2018, Copyright the Authors Journal compilation © 2018, The American Geriatrics Society
PY - 2018/8
Y1 - 2018/8
N2 - Objectives: To describe the psychometric properties of the Picture-based Memory Impairment Screen (PMIS) in a multidisciplinary memory disorder center serving an ethnically and educationally diverse community. Design: Cross-sectional cohort study. Setting: Montefiore Center for Aging Brain (CAB). Participants: Individuals with cognitive complaints (N=405; average age 76±10, 66% female). Measurements: A geriatrician or neurologist administered the PMIS, and a neuropsychologist administered the Blessed Information, Memory, and Concentration (BIMC) test and determined whether participants had dementia, mild cognitive impairment (MCI), or subjective cognitive complaints (SCC). Results: Mean PMIS scores were 4.0±2.6 in participants with dementia (n=194), 6.8±1.5 in those with MCI (n= 155), and 7.0±1.8 in those with SCC (n= 56) (p<.001). PMIS scores showed similar significant linear trends when analyzed according to ethnicity, education, sex, and language. The PMIS was negatively correlated with BIMC score (p<.001). The PMIS had positive predictive value of 77%, negative predictive value of 73%, sensitivity of 68%, and specificity of 81% to detect all-cause dementia in this population of individuals with cognitive complaints. Conclusion: The PMIS is a quick, valid screening tool to identify cognitive impairment in individuals with cognitive complaints that accounts for cultural and educational differences.
AB - Objectives: To describe the psychometric properties of the Picture-based Memory Impairment Screen (PMIS) in a multidisciplinary memory disorder center serving an ethnically and educationally diverse community. Design: Cross-sectional cohort study. Setting: Montefiore Center for Aging Brain (CAB). Participants: Individuals with cognitive complaints (N=405; average age 76±10, 66% female). Measurements: A geriatrician or neurologist administered the PMIS, and a neuropsychologist administered the Blessed Information, Memory, and Concentration (BIMC) test and determined whether participants had dementia, mild cognitive impairment (MCI), or subjective cognitive complaints (SCC). Results: Mean PMIS scores were 4.0±2.6 in participants with dementia (n=194), 6.8±1.5 in those with MCI (n= 155), and 7.0±1.8 in those with SCC (n= 56) (p<.001). PMIS scores showed similar significant linear trends when analyzed according to ethnicity, education, sex, and language. The PMIS was negatively correlated with BIMC score (p<.001). The PMIS had positive predictive value of 77%, negative predictive value of 73%, sensitivity of 68%, and specificity of 81% to detect all-cause dementia in this population of individuals with cognitive complaints. Conclusion: The PMIS is a quick, valid screening tool to identify cognitive impairment in individuals with cognitive complaints that accounts for cultural and educational differences.
KW - cognitive screen
KW - dementia
KW - epidemiology
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U2 - 10.1111/jgs.15422
DO - 10.1111/jgs.15422
M3 - Article
C2 - 29808583
AN - SCOPUS:85047769486
SN - 0002-8614
VL - 66
SP - 1598
EP - 1602
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
IS - 8
ER -