Physiology and pathophysiology of coronary circulation

Andrea I. Guaricci, Luigi Di Biase, Giancarlo Casolo

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The heart supplies blood to itself through two coronary arteries that support the coronary circulation. Both arteries lie outside of the heart muscle running along the atrioventricular groove and branch off into a system of smaller vessels that supply the muscle cells. Because of the high oxygen requirements of the myocardium, capillary density is very high, (accounting for ∼15 percent of the total cardiac mass). After giving off its oxygen and nutrients in the capillaries, the venous blood flows through coronary veins draining directly into the right atrium. Other drainage is by means of thebesian veins, which drain directly into the right heart, and anterior cardiac veins that empty into the right atrium. Small intramural collateral vessels represent functionally important elements that connect the coronaries and can enlarge after coronary obstruction, providing near-normal flow at rest to the distal segment of the diseased artery. When the heart needs to work harder than during basal conditions, the coronary arteries dilate, thus varying the resistance to the blood flow and increasing the oxygen supply to the heart.

Original languageEnglish (US)
Title of host publicationClinical Applications of Cardiac CT
PublisherSpringer-Verlag Italia s.r.l.
Pages7-14
Number of pages8
ISBN (Print)9788847025226, 8847025214, 9788847025219
DOIs
StatePublished - Nov 1 2013
Externally publishedYes

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Coronary Circulation
Physiology
Coronary Vessels
Oxygen
Heart Atria
Blood
Veins
Myocardium
Arteries
Muscle
Oxygen supply
Muscle Cells
Drainage
Nutrients
Food
Cells

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Guaricci, A. I., Di Biase, L., & Casolo, G. (2013). Physiology and pathophysiology of coronary circulation. In Clinical Applications of Cardiac CT (pp. 7-14). Springer-Verlag Italia s.r.l.. https://doi.org/10.1007/978-88-470-2522-6_2

Physiology and pathophysiology of coronary circulation. / Guaricci, Andrea I.; Di Biase, Luigi; Casolo, Giancarlo.

Clinical Applications of Cardiac CT. Springer-Verlag Italia s.r.l., 2013. p. 7-14.

Research output: Chapter in Book/Report/Conference proceedingChapter

Guaricci, AI, Di Biase, L & Casolo, G 2013, Physiology and pathophysiology of coronary circulation. in Clinical Applications of Cardiac CT. Springer-Verlag Italia s.r.l., pp. 7-14. https://doi.org/10.1007/978-88-470-2522-6_2
Guaricci AI, Di Biase L, Casolo G. Physiology and pathophysiology of coronary circulation. In Clinical Applications of Cardiac CT. Springer-Verlag Italia s.r.l. 2013. p. 7-14 https://doi.org/10.1007/978-88-470-2522-6_2
Guaricci, Andrea I. ; Di Biase, Luigi ; Casolo, Giancarlo. / Physiology and pathophysiology of coronary circulation. Clinical Applications of Cardiac CT. Springer-Verlag Italia s.r.l., 2013. pp. 7-14
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